Joanne M said:
I keep reading posts in which upset tummy issues with our cavs are being treated with flagyl, an antibiotic. Tucker was prescribed it twice in one month. The 2nd time I told the vet I had concerns giving Tucker such a powerful antibiotic when his previous stool sample revealed no parasite and there was no other sign of bacterial infection, other than loose and bloody stool on one occasion. The vet told me flagyl was also an anti-inflammatory. It still concerns me, because I've always believed that over prescribing antibiotics had potential side-effects....
karlin, i think that was me, one of my vets said that flagyl has the added benefit of being an anti-inflammatory for the bowel when i asked what was the point of giving it repeatedly.
joanne, zack had bloody diarrhea the day i brought him home. i took him right to the vet, with a stool sample, and flagyl was prescribed. They didn't say to change his diet or anything. The stool sample was negative. They said it won't always show anything but that flagyl usually works. The flagyl worked immediately, the same day i think. no more diarrhea.
I finished giving him the pills for 7 days. Then about a week later, i took him for his last vaccination. He'd already had the other two before i got him. a couple of days after the vaccination, the diarrhea returned. They prescribed the same flagyl again, same dose, same 7 days. The second time it didn't work as fast and on the last of the 7 days, Zack, who no longer had diarrhea, began vomiting and looked sick for the first time, listless, not eating or drinking, took him to the emergency room, went to the vet the next day, they gave him a shot for the vomiting and he was ok for about one day, and then he got bloody diarrhea again. They said to give Flagyl again. This was not making sense to me. I asked why it had worked so well, but then kept coming back, and i was told that one of the fortunate benefits of flagyl was that it had an anti-inflammatory effect on the bowel, independent of antibiotic properties. So apparently, the reason the symptoms cleared up was because the medication treated the inflammation. zack continued to have vomiting and diarrhea. The vet said they could do exploratory surgery or endoscopy, there was nothing else to try.
at that point i went to a new vet. She took him off the flagyl and put him on salicylamide. He seemed better for a day or a day and a half, then vomiting came back and his eyes started tearing. Damage to tear production is the most common side effect of salicylamide. when i took him back to the vet two days later, she added flagyl back and continued salicylamide but reduced the dose, because of the tearing--which he hadn't had before that. He continued to have vomiting every other day, she gave him reglan for that and ointment for his eyes, plus the two antibiotics. But then, she changed the antibiotics to Tylan, which is another one that is an anti-inflammatory for the bowel. It's an antibiotic for hogs and elephants, but it helps with colitis in small animals.
poor little zack, he was full of drugs plus whatever was making him sick, and the drugs weren't helping. The vet said she was "stumped" and said the next thing to try was a barium study ($600 ch-chingggg). She did put him on ID diet but it didn't make any difference. She also
then i went to another new vet. She said to continue to medications he was already on, and she prescribed somehtnig else for the stomach, instead of reglan, pepcid i think, and she also prescribed Dontral Plus, a broad spectrum deworming medication. About the deworming, she said "I'd hate to miss that diagnosis." I was cringing at all these medications, and no improvement after a month and $1000. I waited a couple of days to give him the Dontral Plus, i stopped his other medications first. And i did it at a time when i could be with him and watch him. He did have a strong reaction to the Dontral Plus, he got really hyper and agitated and wasn't himself at all, he coudln't sleep and he was climbing the walls, literally, it lasted all night. BUT, from that day on, there was no more vomiting or diarrha..
I kept waiting for it to come back but it never did.
Throughout this whole thing, i never saw a single worm. but the ordeal was over after the deworming.
Altogether he had 3 negative stool samples, but if i ever have to go through anything like that again, instead of having the stool samples a week apart or whatever it was that i did, next time i will have them on about 4 consecutive days because i've read that it's easy to miss them unless you do that.
He had to take a second dose of the Dontral Plus, that was the prescription. After the reaction he had, i was scared to give it to him again. The vet called the company and they said it occasionally happens, and to break the pill into two pieces, i think, or four. I don't remember now, i gave it to him over a two day period and he didn't have a reaction that i could see.
These drugs are potent chemicals and i relate to your caution about it.