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estelle
28th November 2007, 02:29 PM
The vet was really pleased with Bailey's progress today, it finally seems like the rattle's shifting and there was less fluid again yippeeeeeeeeeee!!!!

She gave him 4 more jabs and we have to go back again tommorow to check his progress, hopefully after that she can send us home with tablets for him instead of having to take him every day for injections!

I just hope he's turned the corner now and things continue to improve.

Will keep updating

Thanks everyone

Karlin
28th November 2007, 02:35 PM
That's great news. :)

Did they definitely eliminate dry eye/curly coat as a possibility? It is very important for them to be throughly aware of this possibility and to make sure this isn't the cause of the eye scarring. :thmbsup:

estelle
28th November 2007, 02:57 PM
How do they test for this? I think now that his chest's clearing she's going to concentrate more on his eyes, she mentioned a test where paper is put into them to test the tear production?

Karlin
28th November 2007, 03:15 PM
You need to talk to your vets. It is a complex syndrome and generally cannot be treated for very long and is extremely painful as it develops -- that is why I said you would have some serious considerations if Bailey turns out to have it. I posted in the original thread and gave you several links. You need to make SURE your vets know about this and how to test for it. They should contact the national CKCS Club if they are unsure what to do.

The paper test will check for how much liquid the tear ducts are producing and is an initial test but only for dry eye. Most vets are not aware of dry eye/curly coat in cavaliers. Some dogs only have dry eye but when a puppy this young has such severe scarring already they really must consider whether it is dry eye/curly coat in combination.

If the puppy has this and you know the breeder you really MUST report them. Talk to the national CKCS Club for advice.

Karlin
28th November 2007, 03:18 PM
From cavalierhealth.org:


Curly Coat -- Rough Coat Syndrome in Cavalier King Charles Spaniels

A rarer but far more severe form of dry eye syndrome in some Cavalier puppies is a combination of dry eye and a congenital skin condition called "curly coat" or "rough coat" syndrome (ichthyosis keratoconjunctivitis sicca). The reference to a curly or rough coat comes from the unusually curly abnormality of the Cavalier's coat which is apparent at birth. However, the puppy also suffers from an extreme version of dry eye, and as the affected dog matures, it develops a deterioration of the skin which results in seborrhea, consisting of skin inflammation and excessive oiliness. Also, the dog's teeth, gums, and other connective tissues may be adversely affected. The form of dry eye associated with curly coat also is rare in that it is of congenital origin.

In cases of curly coat (rough coat) syndrome, nearly continuous daily care, including very frequent medicinal bathing, is required to treat the skin condition, as well as applying the eye medications. In a 2003 study reported by Dr. Keith C. Barnett, OBE MA PhD BSc DVOphthal FRCVS DIpECVO, European Specialist in Veterinary Ophthalmology, the dry eye condition of curly coat dogs may be so severe that cyclosporine therapy is ineffective, and the skin condition progresses into severe lesions. In a September 2006 paper, Dr. Barnett reported that successful treatment of the skin condition is not possible, although there can be some improvement in the dry eye condition.

Dr. Barnett reported that the need for constant care of the eyes and skin may lead breeders to resort to early euthanasia of the affected puppies as the only humane result, to avoid the dogs suffering from lifetimes of extreme discomfort and permanent eye damage.

No cases of the combination of dry eye syndrome and curly coat syndrome have been reported in any other breed. Studies have been conducted in the United States, United Kingdom, Australia, Sweden, the Czech Republic, and Iceland. It is believed to be due to a simple autosomal recessive gene. If so, then affected puppies are more likely to be found in cases of line breeding or inbreeding on carrier bloodlines. During a two year period recently in Iceland, more than half of many litters of Cavalier puppies were born affected by the syndrome. The disorder may be more widespread than previously believed as more owners and veterinarians become aware of its symptoms.

More on dry eye alone here:

http://www.cavalierhealth.org/dry_eye.htm

From the UK CKCS CLub site:


Report of the Eye Sub-Committee - AGM 2006

ICHTHYOSIS KERATOCONJUNCTIVITIS SICCA (Dry eye/curly coat)

There have been 21 separate cases of the condition submitted to the AHT since the research started. This does not take into account the many undiagnosed cases that went unreported due to lack of knowledge. It is now believed that there were in the order of some 39 or more cases that the Michigan State University and the University of Tennessee were aware of. Several cases have occurred in Australia, Sweden and the Czech Republic. Iceland has one of the smallest gene pools and has been unlucky enough to have imported several carriers, to the point that in the period 2002-2003 there were instances of more than 50% of many litters being born affected. It seems to imply that the condition is more widespread that first though as more people come to recognise the symptoms.

Several theories have been suggested, but the most practical seems to be that the condition is inherited, probably by as simple autosomal recessive gene. This means that a percentage of the Cavalier population may be carriers and when two carriers come together and affected puppy could be seen. One would expect this to be in the ratio of one affected, two carriers and one clear. However, there have been numerous cases were half or nearly all of one litter have been affected. It is not yet known whether this is just co-incidence or some other form of inheritance at work. What has been established however is that in an affected puppy's pedigree, a suspected carrier is always identified on both the sire and dam's lines. It would seem that an affected puppy is more likely to be seen where line or inbreeding on carrier lines is carried out.

There is now sufficient pedigree data available and a genetic programme is being carried out by Dr Kathryn Mellersh, a well respected geneticist at the AHT. Twenty seven (27) candidate genes have been identified and the tests are currently in progress and final results are pending.

With written support from the CKCS Club an application was made the Kennel Club for a grant to help with the research into this condition. I am pleased to report that a grant of £4,200 has been approved by the Charitable Trust and payment has been made to the AHT.

This condition is not as widespread as some other health issues but is particularly nasty in its expression. There is no treatment for the condition, only symptom and pain relief management. It is considered by the researches to be a condition best dealt with by euthanasia as soon as it is recognised. I urge all breeders to make themselves familiar with the condition to prevent unnecessary suffering to afflicted puppies.


Link: http://www.thecavalierclub.co.uk/health/eyes/eyes.html

Scouty girl
28th November 2007, 08:20 PM
That's very positive new about Bailey. We will be praying that he gets better everyday.

Elaine 2
29th November 2007, 12:32 AM
We've got everything crossed here for him :xfngr:

estelle
29th November 2007, 12:46 PM
Good news again today for Bailey!! The vet was really pleased today with him and she was happy to send us away with tablets for him. He has 5 days worth and has to go see the vet again on Tuesday.

Yippeeeeeeeeeeeeeee

Just thought i'd keep you updated.

Scouty girl
29th November 2007, 01:33 PM
Wow, that is great news!!!! Keep up the good work Bailey.