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Cathy Moon
6th April 2010, 01:34 AM
Geordie has been taking Lyrica for two days now, and it appears to be working better than Gabapentin for him so far. Still watching closely and trying to be objective. He has completely stopped his bending/twisting behavior today (after his initial 6:00 am pill), he likes to be petted on both left and right sides, and he likes to be picked up and cuddled. He also seems much more bright eyed and active, much calmer and nicer at feeding times, too. He used to seem very desperate at mealtimes (similar to how Charlie, our other cavalier with SM was), and he wasn't that way when he was younger.

We're continuing to watch him, though, and he has a 2 week followup appointment with the neurologist. :xfngr::xfngr::paw::paw::paw:

Cathy T
6th April 2010, 01:38 AM
That's great Cathy!! I know Terri saw a big difference with Friday on Lyrica. Fingers crossed for continued relief for Geordie.

arasara
6th April 2010, 03:00 AM
Good to hear! I'm glad it seems to be working :) Fingers crossed it keeps up! :)

Nicki
6th April 2010, 09:38 AM
oh thank goodness that's great news Cathy :D

I really hope it continues to work well for Geordie.

*Pauline*
6th April 2010, 10:55 AM
This is great news for you and Geordie Cathy and interesting to those with SM dogs. Is this available in the UK?

Karlin
6th April 2010, 12:20 PM
Yes, it is available in the UK -- Clare Rusbridge and other neurologists would regularly prescribe it for dogs when gabapentin isn't working very well. It is actually a stronger variation on gabapentin.

Great to see some positive signs Cathy. :hug: Fingers crossed this gives some helpful relief. :)

Karlin
6th April 2010, 12:26 PM
Gabapentin vs pregabalin (Lyrica):

http://www.crpsadvisory.com/crpsa_pregabalin_vs_gabapentin.html

*Pauline*
6th April 2010, 12:28 PM
Thanks Karlin, I didn't know Lyrica was Pregabalin. Will read up on it.

*Pauline*
6th April 2010, 12:35 PM
Have read the link you posted Karlin and am very impressed. I wonder if this is our next step.

Karen and Ruby
6th April 2010, 02:21 PM
It is definatly worth a try if results arent being seen on gabapentin. Ruby has been on it since september and is still doing fantastically well- some days i give her half the amount!

Im so pleased your results have been so quick- they were for us aswell, its my little miricle drug for sure

I hope he continues to do well on it!!!

Tania
6th April 2010, 02:49 PM
Great news Lyrica is helping Georgie, it must be a relief for both of you.

Cathy Moon
7th April 2010, 01:49 PM
Thanks for posting the link, Karlin.

Pregabalin/Lyrica is significantly more expensive than Gabapentin in the US, Gabapentin is on the government [subsidized?] list of generics at $.09 per capsule, while we've just paid $2.96 per capsule for Lyrica. I will call around when we get our next prescription filled to see if we can find a better price.

Geordie seems happier and more playful. He is staying in the same room with the rest of us, rather than going off to the bedroom to lie down in his favorite bed alone.

*Pauline*
7th April 2010, 03:19 PM
This sounds a very positive result Cathy, I'm really happy for you and Geordie.

Karlin
7th April 2010, 08:36 PM
The main difference is that gabapentin is now a generic medication full stop and others can make it hence the price has dropped, while Lyrica will be under patent for some time yet and thus will remain expensive. Wow is that 2.96 per 25mg capsule (eg the lowest dose)? Ouch.

Gabapentin remains very costly in Ireland though and you can never find the generic version. :|

Karen and Ruby
8th April 2010, 10:45 PM
Ive found mine for 1.86 per capsule (50mg) which is by far the cheapest I have found but thats not very helpful for you on the other side of the pond :o

Cathy Moon
11th April 2010, 12:17 AM
Wow is that 2.96 per 25mg capsule (eg the lowest dose)? Ouch.
Yes, basically it's costing $6.00 per day. :eek: This is a three month prescription right now, so the next time I'm going to spend a lot of time on the phone calling around for prices.

It will be interesting to compare the cost when the liquid formula is available. The neurologist would have liked for Geordie to be at a lower dose, but I think it would have been 3 times per day if we could have gotten the liquid suspension.

Cathy Moon
15th April 2010, 05:06 AM
We've just been given permission to increase Geordie's Lyrica to every 8 hours. :( He has been bending and scratching again, and he stayed in his bed in our bedroom alone most of yesterday. I'm praying this will make him more comfortable.

He still has times when he runs and plays, though. I wonder if he and India play too rough. And I wonder if I should let him play with India outside, or let them outside separately so he won't run.

When our dogs have SM, should we treat them like they're injured and limit their activities -or- let them play, even though they pay for it later???

Jane P
15th April 2010, 08:58 AM
When our dogs have SM, should we treat them like they're injured and limit their activities -or- let them play, even though they pay for it later???

I'm so sorry to hear Geordie's having problems. Dylan's on Lyrica plus NSAIDs and furosemide and most of the time he limits himself and rarely plays with Harvey or runs about any more but when he does he pays for it later. I too worry how much should I restrict his activity whilst ensuring he still has some quality of life. I try to keep him as calm as possible and avoid situations where he may become stressful of excited.

I hope the increase in Lyrica helps Geordie.:hug:

Nicki
15th April 2010, 12:58 PM
Oh Cathy I'm so sorry - I really hoped this was the answer and Geordie would continue to do well.
:hug::hug:


That was always the eternal question for me - do you confine them so that they don't have such a good quality of life - or do you let them enjoy the time they have left?

We tried to strike a balance - Teddy until the last few weeks wanted to go for and enjoyed his walks - but we kept it to 2 or 3 per week, as it would make him worse.

That's all I can suggest - that you let them have some free time but not all the time.

Once you get to the point where you are confining them most of the time and they are not free to enjoy walks or the garden anymore, then that for me is not sufficient.

jacies
15th April 2010, 05:04 PM
Hi Cathy, sorry to hear you are still having problems getting Geordie's meds sorted. Chaos is not on Lyrica yet, just as well really as I could not afford the price, and is still on Gabapentin. Was wondering if he was on any other type of medicine. Chaos is also on prednisolone, now reduced to 1/2 tab every other day and that did help, but not what you would want to add if you dont have to. I think the one thing that made a big difference to her though was the Tramadol which she now has twice a day. Before that she would also hide herself away and her eyes always looked so sad like she was in pain. Now I can see a big difference in her, her eyes are clear and sparkling and she seems altogether happier and does not take herself off on her own. I am not sure exactly what the difference is but think the different types of meds work on different symptoms or type of pain.
I do let her run free in the garden and walk her every day on a long lead and she really enjoys her walks and they do not seem to affect her afterwards. For the first part of the walk she travels in her stroller, I am not sure why she doesn't want to walk to begin with but she lets me know when she is ready to get out and then is off like a steam train. The one thing I now stop her from doing is swimming as that definitely affected her adversely. Six months ago I thought I would not have her much longer as she was so bad so I hope you can find the solution for Geordie.

Cathy Moon
16th April 2010, 03:26 AM
Thanks for your responses. I think we will only let him run and play with India every 3 days or so, but maybe I'll try to walk each of them instead of allowing their roughhousing.

He was sleepy today, but he seems more comfortable. :xfngr::xfngr::paw::paw::paw: Fingers and paws are crossed for good results. He's definitely interested in what's going on when he's awake - he was just up on the love seat looking out the window.:)

Cathy Moon
14th September 2010, 01:52 AM
It has been several months now, and Geordie had been doing ok on the 25 mg Lyrica every 8 hours, having mostly good days and some bad days where I had to give him Metacam in addition to the Lyrica.

In August I was giving him Metacam more often than not, and even with that he was still curving his body and scratching his neck/shoulder. We contacted his neurologists at Ohio State University; they let us give Geordie a double dose of Lyrica that night, and we got an emergency appointment for the following day. He was given a full exam, and found to be stable neurologically, even though his syrinxes are severe.

There was some discussion about putting him on a short course of prednisone, but it could not be started until the Metacam was totally withdrawn for a week. Since he had done so well with the 50mg dose of Lyrica the night before (I woke up to check him all night) and during that day, he was allowed to continue on it following a blood panel that shows he's in normal ranges for all the tests. We were told to try giving him 50 mg every 12 hours, or every 8 hours if he seemed to need it.

What we've found is that 50 mg Lyrica every 12 hours is what works best for him (he weighs about 18 lbs). He is playing every day now, and snuggling up with me in my big chair in the evenings. He had another follow-up appointment in early September, and we decided not to give him Prednisone since he is doing so well, and because he had a gatrointestinal upset last time he had it in the past.

There isn't very much information available about Lyrica dosage for dogs, so I'm hoping this information will be helpful to someone. I was most fortunate to have information about Lyrica dosage from Terri and her little cavalier Friday to share with our neurologists. :thnku: Terri!!!!