anniemac
Well-known member
I am trying to put together some information for my blog and also give it to another blogger who actually has more people read it (not just Cavalier owners).
I read Dr. Rusbridge article on http://www.asap.org/index.php/medical-articles/canine-syringomyelia/
and wanted to know if there is anything to add to this:
"
How does this help human sufferers? There are many possibilities:
Obviously if people know the research may also benefit humans as well as other breeds. We can reach a bigger donation pool :xfngr: or even to raise awareness on its on is good.
Karlin, Nicki, Tania, can you give me more information or is this pretty much the most up to date. This was not found on the American Syringomyelia & Chiari Alliance Project.
I read Dr. Rusbridge article on http://www.asap.org/index.php/medical-articles/canine-syringomyelia/
and wanted to know if there is anything to add to this:
"
How does this help human sufferers? There are many possibilities:
- Understanding the genetics. Chiari malformation is inherited in this breed and, if the causal gene or genes could be identified, then scientists could study what this gene does and why Chiari malformation and syringomyelia develop. Clare Rusbridge and her team, with considerable help from Cavalier breed clubs and owners, have established a worldwide DNA collection from affected dogs and their families. They now have over 800 samples and are working with a neurogenetics laboratory in Montreal with the ultimate aim of finding the gene(s).
- Better understanding of the symptoms. Why are some dogs/people so much more painful than others? Why do some not make the expected improvement after surgery? Why do some patients have an intensification of pain after surgery? These are all questions that study of the dogs could help answer.
- Understanding how and why syringomyelia develops. In some litters of Cavalier puppies, it is highly likely that most will develop syringomyelia. These dogs could be studied, i.e., with serial MRI scans from an early age before and after the syringomyelia has developed. As a natural model of Chiari malformation, these dogs can provide useful information
- Improving treatment of both people and dogs. Better understanding of the disease leads to the possibility of more effective drugs and surgery. The Cavaliers in question are loved pets and are cared for by veterinary neurologists. They vastly outnumber human patients so there is a greater possibility to learn from successful experiences and apply these to humans. Similarly, human sufferers can provide dog owners with an understanding of what their pets can be experiencing and ensure they are provided with care.
Obviously if people know the research may also benefit humans as well as other breeds. We can reach a bigger donation pool :xfngr: or even to raise awareness on its on is good.
Karlin, Nicki, Tania, can you give me more information or is this pretty much the most up to date. This was not found on the American Syringomyelia & Chiari Alliance Project.