View Full Version : About Parvo - The Parvo Hysteria
9th January 2012, 02:16 PM
Just seen this. What do people think? I find it shocking that Parvo is man made.
[full article removed by Admin (see below). Can you provide the direct link instead, Sabby? :) - Karlin]
9th January 2012, 02:45 PM
All I know about parvo is that we had it in my street. 3 dogs died - 2 puppies that hadn't finished their vaccinations, and 1 unvaccinated adult. My vaccinated Cavalier was OK, although we were regularly walking along the street - I did wipe paws and shoes in disinfectant coming back into the house. It's not just puppies that can be at risk, elderly dogs are also vulnerable. However it came into being or spread, parvo today is a killer and we have regular outbreaks in the Midlands, so we need to take care of our dogs.
I was surprised after all that science that the writer described himself as 'a strong advocate of treating the dog with respect for its nature as domesticated wolf' - very out-of-date! The latest research says that dogs are not directly closely-related to modern wolves - they share a common ancestor and therefore DNA but dogs and wolves have evolved very differently over the centuries. Apparently the nearest wild link to the dog today is a Golden Jackal!
Kate, Oliver and Aled
9th January 2012, 03:39 PM
I love how he blames the breeder:
"I brought home a new puppy some years ago from what I thought was a
responsible breeder: In accordance with our contract, the breeder was not supposed to vaccinate the puppy. But she did - on the very day I came to pick it up... 5 weeks later, this little female almost died from parvo; in 9 days, her
weight went from 9 kg below 5 kg. She literally lived on IV and did not move at all for over a week...."
Parvo incubation is 3-10 days, obviously this person is against vaccination and didn't get a 2nd booster, she has no evidence that if she got a second booster that her dog would have still gotten parvo, she also suggests that dogs who don't get the vaccine do not get parvo "I never saw a case of Parvo among the dogs that were not vaccinated"
Hello! They brought parvo to his puppy class! My puppy class is at my Vet and it is exclusive so that only puppies that go to my vet are allowed in the class, so the vet knows if every pup has had its shots. They ask us questions like "Has she been in contact with any other dogs, do you take her walking etc. Obviously he wasn't so selective, which brings me to my last point HE has not let us know whether he allowed her puppy that died to have contact with other dogs, and it is common knowledge amongst knowledgable pet owners that the first booster does little more than kill the immunity from its mother which is why there are 2 more shots! :mad:
9th January 2012, 03:42 PM
Take that article with one HUGE grain of salt. :rolleyes:
Also have deleted it as it's a copyright issue to reprint an entire article without permission -- providing a link is fine. :thmbsup:
9th January 2012, 03:55 PM
Just to add: ask anyone in rescue: the single biggest threat to litters of unvax'd puppies is... parvo. Number one killer of unvax'd puppies in pounds... parvo. A puppy has, like a human child, a totally immature and barely formed immune system when young so of course is going to be succeptible to serious diseases more so than an adult. That is why children not adults died in huge numbers from well-documented CHILDHOOD diseases like whooping cough, measles, mumps, polio before there were vaccinations. Good immune systems are in some part, genetic as well anyway, not related to how healthy anyone is at any given time. Anyone who claims to know anything about vaccination knows that a puppy can easily die after a first vaccination for parvo -- that's why two and sometimes three shots are given and it is called the puppy *series* vaccinations... and needs the one year booster too.
I'd recommend people always have the skeptic filter on when visiting random websites -- and look for some sensible confirmation elsewhere before getting worried about claims like this. :flwr:
9th January 2012, 06:01 PM
Thats the link. (If it works)
K9joy Education: free article on The Parvo Hysteria by Mogens Eliasen (http://k9joy.com/dogarticles/parvo.php)
What gets me is that Parvo is a man made virus.
9th January 2012, 06:26 PM
It isn't. Viruses mutate all the time from existing viruses and jump species as well. It was not manmade.
9th January 2012, 06:30 PM
Take that article with one HUGE grain of salt. :rolleyes:
That article is not just "BS," but it is one huge crock of doggie diarrhea. It was first published in 2005 so it is old news.
Parvo is not a "man-made virus." It is a variant of feline panleukopenia.
Try these for the etiology of parvo:
Vet Microbiol. 1999 Sep 1;69(1-2):29-40.
Host range relationships and the evolution of canine parvovirus.
Canine parvovirus (CPV) is an example of an unusual class of emerging virus-those that gain an altered host range through genetic variation and subsequently become widespread pathogens of their new and previously resistant host species. CPV was first detected in 1978 as the cause of new diseases in dogs throughout the world, when it rapidly spread throughout domestic populations, as well as becoming widespread in wild dogs. CPV was soon shown to be a variant of the long recognized feline panleukopenia virus (FPV), from which it differed in less than 1% at the nucleotide sequence level. Genetic analysis showed that virtually all of the biological differences between CPV and FPV, including the canine host range, were determined by three or four sequence differences in the viral capsid protein gene. Analysis of the atomic structures of the CPV and FPV capsids showed that the differences controlling host range were located within two different structural regions and were exposed on the capsid surface. The CPV which first emerged in 1978 appeared to be derived from a single ancestral sequence, which has allowed the ready analysis of the subsequent evolution of the virus in nature. Sequence analysis has also revealed that CPV strains have undergone a series of evolutionary selections in nature which have resulted in the global distribution of new virus variants. This was first seen in the global replacement between 1979 and 1981 of the original (1978) strain of the virus by a genetically and antigenically variant strain, and the subsequent widespread selection of other variants which have also become globally distributed. The genetic and antigenic variation in the virus strains was also correlated with changes in the host range of the virus, in particular in the ability to replicate in cats, and in canine host range differences seen in tissue culture cells.
J Vet Med B Infect Dis Vet Public Health. 2005 Sep-Oct;52(7-8):303-11.
An annotated historical account of canine parvovirus.
A brief annotated history of canine parvovirus-type 2 (CPV-2) and its variants is summarized with emphasis on the most significant contributions of individuals involved in the initial recognition of CPV-2 and subsequent discoveries that have advanced our knowledge of the nature and evolution of this novel canine virus. Time has obscured the observations of many veterinary clinicians and researchers throughout the world who sensed the presence of a new disease when CPV-2 first made its appearance in 1978 and then, within 1-2 years, spread worldwide. Since 1979, nearly 600 articles, papers, numerous text chapters and monographs have been published on the subject of CPV-2. The early history is well known by veterinary infectious diseases specialists and noteworthy publications are recorded on the National Library of Medicine (USA) website, PubMed and in review articles. Because of the great number of publications, it is not practicable to cite them individually; however, reference is made to certain individuals, reviews and selected papers that I consider particularly relevant to the history of progress in the understanding of CPV-2 and the disease it causes. The clinical disease caused by CPV-2 and its variants, the immune response to infection or vaccines, host range and the development of practical diagnostic assays are noted in historical context. The basic biological properties and the physical, molecular and antigenic structure of CPV-2 and its variants are also discussed briefly. Finally, key players who have contributed to the antigenic and DNA sequence (evolutionary) relationships between CPV-2 and the other autonomous parvoviruses of carnivores are noted and hypotheses regarding the origin and evolution of CPV-2 and its variants are mentioned.
9th January 2012, 06:30 PM
Canine parvovirus (CPV) and feline panleukopenia virus (FPLV) are members of the feline parvovirus (FPV) subgroup and are classified as autonomous parvoviruses of the familyParvoviridae (23 (http://cvi.asm.org/content/8/3/663.full#ref-23)). CPV type 2 (CPV-2) was first observed in dogs in 1978, and this virus subsequently became globally distributed such that it is now endemic in populations of domestic and wild canids (16 (http://cvi.asm.org/content/8/3/663.full#ref-16), 22 (http://cvi.asm.org/content/8/3/663.full#ref-22)). The origin of CPV-2 has not yet been identified, although various hypotheses explaining its derivation and sudden emergence have been proposed. The most widely accepted hypothesis for its emergence is that CPV is derived from FPLV in cats or from FPLV-like viruses in wild animals by natural genetic mutation. Genetic analyses of parvovirus DNA obtained from a number of wild carnivore isolates might support the latter hypothesis (26 (http://cvi.asm.org/content/8/3/663.full#ref-26), 30 (http://cvi.asm.org/content/8/3/663.full#ref-30),31 (http://cvi.asm.org/content/8/3/663.full#ref-31)).
Parvovirus CPV2 is a relatively new disease that appeared in the late 1970s. It was first recognized in 1978 and spread worldwide in one to two years. (http://en.wikipedia.org/wiki/Canine_parvovirus#cite_note-1) The virus is very similar to feline panleukopenia (http://en.wikipedia.org/wiki/Feline_panleukopenia) (also a parvovirus (http://en.wikipedia.org/wiki/Parvovirus)); they are 98% identical, differing only in two amino acids in the viral capsid (http://en.wikipedia.org/wiki/Capsid) protein VP2. (http://en.wikipedia.org/wiki/Canine_parvovirus#cite_note-Carter-2) It is also highly similar to mink (http://en.wikipedia.org/wiki/Mink)enteritis, and the parvoviruses of raccoons (http://en.wikipedia.org/wiki/Raccoon) and foxes (http://en.wikipedia.org/wiki/Fox). (http://en.wikipedia.org/wiki/Canine_parvovirus#cite_note-Jones1997-3) The early belief was that the feline panleukopenia mutated into CPV2. It is possible that CPV2 is a mutant of an unidentified parvovirus (similar to feline parvovirus (FPV)) of some wild carnivore. (http://en.wikipedia.org/wiki/Canine_parvovirus#cite_note-Hirayama-4) A strain (http://en.wikipedia.org/wiki/Strain_(biology)) of CPV2b (strain FP84) has been shown to cause disease in a small percentage of domestic cats (http://en.wikipedia.org/wiki/Cat), although vaccination for FPV seems to be protective. (http://en.wikipedia.org/wiki/Canine_parvovirus#cite_note-5) CPV2, however, does not cause disease in cats and does so only mildly in mink and raccoons, and is a virus almost exclusively affecting canines.
(http://en.wikipedia.org/wiki/Canine_parvovirus#cite_note-Jones1997-3)Two more strains of canine parvovirus CPV2a and CPV2b were identified in 1979 and 1984 respectively. (http://en.wikipedia.org/wiki/Canine_parvovirus#cite_note-Hirayama-4) Most cases of canine parvovirus infection are believed to be caused by these two strains, which have replaced the original strain, and the present day virus is different from the one originally discovered (http://en.wikipedia.org/wiki/Canine_parvovirus#cite_note-Jones1997-3) (http://en.wikipedia.org/wiki/Canine_parvovirus#cite_note-6) although they are indistinguishable by most routine tests. A third type, CPV2c (a Glu-426 mutant (http://en.wikipedia.org/wiki/Mutant)), has been discovered in Italy (http://en.wikipedia.org/wiki/Italy), Vietnam (http://en.wikipedia.org/wiki/Vietnam), and Spain (http://en.wikipedia.org/wiki/Spain). (http://en.wikipedia.org/wiki/Canine_parvovirus#cite_note-7)
9th January 2012, 06:39 PM
*snap* -- Pat we both posted at the same time... on this ridiculous article which still can mislead and unnecessarily worry people.:mad:
Never was a site so inappropriately named. :rolleyes:
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