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Brian M
17th July 2012, 04:10 PM
Hi

We saw her neuro last night for a progress check ,I advised she is still scratches occasionally, but not a lot, and that her
medication of 2x100 mg Gabapentin from what I can see has not really made any great change to her scratching .I requested
a possible increase of the Gabapentin from 2 daily to 3 but her neuro wanted to include Omeprazole into her meds and of course
did not want to vary two meds at the same time so it was decided to proceed with the inclusion of the 10 mg of Omeprazole for
a three week trial then possibly increase the Gabapentin to 3x daily if needed .Her daily meds are now 3x50 mg Zitac ,2x100 mg
Gabapentin and 1x daily of 10 mg Omeprazole .I asked why would she take both the Zitac and Omep if they are both CSF reducers
and was advised that the Zitac acts as a fluid reducer and the Omep acts to try and reduce the production of spinal fluid ,am I right here or am I suffering from information overload . Any comments ,thoughts,advice or guidance most welcome please .

Daisy unfortunately has what was a small pimple on her left side which has now developed into a larger fibrous cyst/wart which I know has to be removed so I have arranged an appointment with a surgeon at C/Gates right after we see her neuro in three weeks time ,so tonight its off to my local Vets with Daisy to ask for a referral letter to them on the grounds that as she has a Grade 4 murmur I would like C/Gates to operate as they have a full time anaesthetist and a complete range of emergency equipment . My poor Daisy .:(

My Dawn's hospital appointment last Friday resulted in the endoscophy finding more ulcers some of which are still bleeding and with her
colonoscophy she found it to be too painful halfway through the procedure and told them to stop. So she has been summoned back to
see her consultant who wants her to have the colonoscophy again ,we go on .:(

MomObvious
17th July 2012, 05:16 PM
Wow Brain, you always seem the have your hands full. Just keep doing what you're doing :)

Melissa

karen baker
17th July 2012, 10:56 PM
Hello Brian, sorry your going through so much lately, with your family, i work in theatres, unfortunately sometimes with colonoscopys patients find this procedure very uncomfortable, everyone is different, did she have sedation? Hopefully next visit they will offer her additional painkiller. My thoughts are with you. Karen Ruby and Sadie :hug:

team bella
17th July 2012, 11:05 PM
Sorry things are tough Brian, sending you and your family positive thoughts and love. Can't they give Dawn an anesthetic to help with the colonoscopy?

Sydneys Mom
17th July 2012, 11:16 PM
Sending good thoughts to all of you and hope all the medical issues get sorted out in the best possible way.

Brian M
18th July 2012, 10:35 PM
Hi

Thanks Joyce you are a star and a best mate .I have been in from work since 6.00 pm and I haven't seen my Daisy scratch once.
Team bella I think thats there next plan ,thanks for caring .

Brian M
22nd July 2012, 10:10 PM
Hi

Daisy has been on her omeprazole for almost a week together with her Zitac and Gabentin and she is a different girl .HURRAH :*nana::jmp::dogwlk:

Sabby
23rd July 2012, 10:21 AM
Hi

Daisy has been on her omeprazole for almost a week together with her Zitac and Gabentin and she is a different girl .HURRAH :*nana::jmp::dogwlk:


So glad that it is helping. I know how you are feeling. I sometimes feel like pulling my hair out with this dreaded SM.

tupup
23rd July 2012, 04:03 PM
Thats great news Bri:D so glad Daisy is more comfortable,bless

keep yer chin up& very best wishes to your Dawn x

Kate H
23rd July 2012, 04:06 PM
So often dealing with SM seems to be faffing around trying this and that until you stumble on the right mix and dosage of medication for your particular dog. Glad you've found it for Daisy (at least for the moment - no doubt it will need tweaking at some future date!).

Kate, Oliver and Aled

Sydneys Mom
23rd July 2012, 04:52 PM
What good news! So glad to hear this! :jump:

Brian M
23rd July 2012, 09:36 PM
Hi

Thanks all for your kind comments ,my Daisy remain a scartch free zone but her snoring has gone up three notches is this a counter balance I wonder .

My Dawn reported another severe nose bleed this morning which tells me she is still losing blood from her tummy ,we ggo back on Thurs pm to her consultant
to see where we go from here .

Brian M
6th August 2012, 11:56 AM
Hi

Dawns been to her consultant and she has her sedated Colonoscophy on the 3rd Nov and starting tomorrow a course of six Vit B12 injections one every other day then one every three months till whenever .Onward we go .

We also take Daisy tomorrow to her Neuro and Surgeon at Chestergates for a look at her lump and how to sugically remove it and a check up on her SM medication .

Margaret C
6th August 2012, 12:36 PM
I hope the injections helps Dawn feel stronger. The sooner she gets that colonoscopy done the better.

Fingers are crossed that Daisy gets sorted out soon.

Brian M
7th August 2012, 08:46 PM
Hi
We went to see Daisy's Neuro today and she is pleased with her progress and we leave her as she is and return in 3 months . After Ulrike we saw Francois the soft tissue
expert ,he spoke and asked questions about Daisy for a good 30 mins before a very thorough all over medical .He advised me about all the types of lumps and the problems
faced with her Grade 4 murmur if we proceed with surgery under a very carefully monitored GA ,he then proceeded to do a needle aspiration and to ring me tomorrow with the results .I think whatever the result, but hope its just something like a sebaceous cyst and not anything that begins with a c we will remove as if it continues over time getting larger and Daisy's murmur gets worse we will have a bigger problem so we decided now is the time for removal and as I say if its sebaceous or fatty we remove a small amount of tissue if its more serious we remove a larger amount of tissue but I don't want the risk of not operating now as it is .The appointed day is Friday ,any thoghts please .
I do so pray my decision is the right one pls

thks

brian

Sydneys Mom
7th August 2012, 09:06 PM
Hi Brian,

Any decision you make for Daisy will be the right one. I know all your decisions about the health and welfare of your girls are made with great thought, research and consideration to their well being. I know you are worried, but do not doubt yourself.

So glad Daisy's Neuro appointment went well. I will keep my fingers crossed for a good outcome on the biopsy. Let us know tomorrow when you hear the results.

jasperpaw
8th August 2012, 08:05 AM
I think you are very right in your decision for Daisy to if necessary have a removal, as you say the problem will only getter worse if the murmur gets worse, as she gets older as there is always a risk with a GA. This is the reason why we cancelled Jasper`s pet insurance a year ago and just save the money for his medication, as we know with a 12 year old dog with a grade 6 murmur, he could never have an operation, but luckily he is jogging on quite nicely on a day to day basis. Hope all goes well with Daisy.

Brian M
8th August 2012, 07:55 PM
Hi
Daisy's Bump
Francois the soft tissue surgeon just phoned the lump is not cancerous ,Thank Heavens ,he told me the type of lump it was but I couldn't get my head around his French accent and my O Level german/latin is no help .We operate on Friday at 10.30 morning he will remove an area about 25 mm in diameter of soft tissue, Daisy will be under just enough anaesthetic to knock her out and depending on Dangerous Daisy's recovery she may come home Friday night or latest saturday morning ,Francois also said that because of the type of lump it is it probably would continue growing but would he not expect it to return after removal.Francois has also worked with the one and only Simon Swift and that because of Daisy's Grade 4 heart murmur he will have the head of anaesthesia present and his main areas of interest are cardio-respiratory emergencies, neuroanaesthesia .I hope my decision is the right on

lindylou
8th August 2012, 08:40 PM
hi
i will be thinking about daisy on friday and hope everything goes alright for her
give daisy a big kiss and cuddle from louie and his mum

pkt89
8th August 2012, 10:13 PM
Hi
I hope my decision is the right on
Brian,
It is the right decision. Good luck on Fri and speedy recovery.
Kitty

Sydneys Mom
8th August 2012, 11:06 PM
Will be thinking of you on Friday and pray for Daisy's speedy recovery.

Margaret C
8th August 2012, 11:33 PM
It is the best decision. If you go to a Specialist it would be foolish not to take their advice.


I'll be thinking of Daisy on Friday.

MomObvious
9th August 2012, 12:13 AM
How come our trouble maker kids always give us a fright???? :) I'm thinking about Daisy and the whole crew. I'm sure she'll be back to her "dangerous" self quickly.


Melissa

Brian M
10th August 2012, 09:33 AM
Hi
Dropped Daisy off at Chestergates but don't you feel a right mean sod when they look at you with those big brown eyes and say "Pls don't leave me here " they know exactly what you are doing .I confirmed that what when they operate at 10.30 the specialst in anaesthesia will be there with her .Come On DAISY .

jasperpaw
10th August 2012, 12:34 PM
Poor Daisy, hope everything went well. I know what you mean about leaving them and going to the vets, although ours have never had an operation, Jasper has had an overnight stay and tests where he had to be left and it felt so awful, Jasper hates the vets and just seems to know that it`s a vet visit when he gets in the car, don`t quite know how, but he gets very agitated. I expect it will seem like a long day for you today.

Brian M
10th August 2012, 01:52 PM
Hi.
Operation done she is breathing nicely Francois is happy all of lump removed and pick her up at 5.30 .Well Done Daisy.

Sydneys Mom
10th August 2012, 02:25 PM
Glad to hear this. Daisy will be her old self in no time! You must be so relieved this is all over.

Brian M
10th August 2012, 09:18 PM
Hi, Daisy is home and now asleep on a cool hdwd floor just by an electric fan ,she had her tea as normal and in addition to her three SM meds she has Ceporex an antibiotic and Loxicom an anti inflammatory .She cannot run or jump and exercise is on a lead for 20 mins max daily for three weeks she also has an Elizabethan collar to wear ,but that's got no chance .The big plus is that the wound and stitches are on the opposite side to her SM scratching side and so far she has totally ignored the wound and covering bandage which I remove tomorrow .We go back to see Francois a week on Tues for stitches out ,final check up and discharge and Francois says "We are very pleased with Daisy's recovery however she remains a critically ill patient and need careful monitoring " so when she moves her servant attends ready to carry her .I am immensely pleased with her and Chestergates and especially the very good and kind Francois and also our Ffon for giving me the confidence in him .Daisy says she is tired its been a long day so thank you all for your kind thoughts and wishes --nite nite .zzzzzzzzzzzzz

http://farm9.staticflickr.com/8282/7754913204_d8d7835f4f_c.jpg (http://www.flickr.com/photos/22730263@N07/7754913204/) Poor Daisy (http://www.flickr.com/photos/22730263@N07/7754913204/) by brianmurtagh49 (http://www.flickr.com/people/22730263@N07/), on Flickr

RodRussell
10th August 2012, 09:47 PM
She's a sweetie. Been through a lot today.

Sydneys Mom
10th August 2012, 10:05 PM
Awwwwwwwww, poor Daisy, it's good she's home. Sending lots of very gentle hugs.

Spangly
10th August 2012, 10:40 PM
Welcome home sweet Daisy. You will get even more fussing from your dad than usual.
Gentle hugs from Spangle.

Love my Cavaliers
10th August 2012, 10:41 PM
Daisy doesn't look too pleased in that picture, but I can see Poppy's tail right there probably trying to keep her company and keep her from mischief. Hopefully she'll have a good night's sleep. That is one huge bandage!! Glad she pulled through OK. Anesthesia is always a worry.

MomObvious
10th August 2012, 11:24 PM
Sweet girl. I'm sure the rest of the girls are happy she is home too. Get well soon!!!

Melissa

lindylou
11th August 2012, 12:53 PM
hi brian
so pleased to hear daisy is home and everything went to plan
daisy is not to happy in the photo but she has gone through an operation
im sure you will give her the best after care and with lost of love
speedy recovery daisy you are 1 beautiful girl
sending you kisses and cuddles from louie and his mum

Brian M
13th August 2012, 09:08 AM
Hi
Very pleased to report Daisy has taken everything in her stride and acts and behaves as though absolutely nothing has happened, and she wonders what all the fuss is about .She has neither licked or even looked at her wound so there has been no need for the Elizabethan collar ,she has been on short walks with the others but I do carry her up and down stairs and on and off the bed as needed .We go back next Tues for stitches out ,and that's another episode over and thankfully a happy ending .

Thanks and Best Wishes
Brian m

Brian M
14th August 2012, 09:32 PM
Hi

Daisy is feeling better.

http://farm9.staticflickr.com/8304/7783526194_72b634b2d4_c.jpg (http://www.flickr.com/photos/22730263@N07/7783526194/) Daisy's Better 2012 (http://www.flickr.com/photos/22730263@N07/7783526194/) by brianmurtagh49 (http://www.flickr.com/people/22730263@N07/), on


]http://farm9.staticflickr.com/8284/7783537958_3f0f39c992_c.jpg (http://www.flickr.com/photos/22730263@N07/7783537958/)
Daisy's Wound August 2012 (http://www.flickr.com/photos/22730263@N07/7783537958/) by brianmurtagh49 (http://www.flickr.com/people/22730263@N07/), on Flickr

Emkaybee
15th August 2012, 07:49 PM
Her face looks nice and relaxed in the picture---glad she's better!

anniemac
17th August 2012, 02:40 PM
Brian,

I've been following Dangerous Daisy's progress but have not posted in some time. I want you to know I've been thinking of you, Dawn and Daisy. I am so glad that Daisy is doing better! As always her pictures are stunning and she always puts a smile on my face. Thinking of you :)

jasperpaw
17th August 2012, 06:43 PM
Great that Daisy is now on the road to recovery. Such a beautiful photo of her as usual.

Brian M
17th September 2012, 08:24 PM
Hi

I have noticed Daisy is drinking a lot more what med could be causing that ?.I also noticed after forgetting to give her 6 pm Gabapentin that
missing it did not seem affect her and this was about ten hours after her 6am one ,so it crossed my mind are the Gabapentin actually doing anything
for her and also as it was only when she went on Omeprazole that I noted a huge reduction in her scratching .I shall of course ask her Neuro when we
go back for her three month assessment in a couple of weeks .Any thoughts please .

Sabby
19th September 2012, 05:50 PM
Hi

I have noticed Daisy is drinking a lot more what med could be causing that ?.I also noticed after forgetting to give her 6 pm Gabapentin that
missing it did not seem affect her and this was about ten hours after her 6am one ,so it crossed my mind are the Gabapentin actually doing anything
for her and also as it was only when she went on Omeprazole that I noted a huge reduction in her scratching .I shall of course ask her Neuro when we
go back for her three month assessment in a couple of weeks .Any thoughts please .


A few times I have forgotten to give Ebony her Gabapentin and nothing happened, but then on other days she needs it every 5 hours otherwise she starts scratching. Ebony has been on Gabapentin for 15 month now and I have not seen any increased drinking.

Best to ask the Neuro.

Brian M
19th September 2012, 08:30 PM
Hi Sabby

Thank you for my reply .

Kate H
19th September 2012, 08:54 PM
Hi Brian

The average time it takes for Gabapentin to pass through the body (metabolise) is 8.5 hours. This means that some dogs, like Sabby's Ebony, may take only 5 hours, others will take 12 hours, so it may just be that Daisy is at the top end of the scale. But how much Gabapentin helps a particular dog can vary - for some it is a miracle drug, for my Oliver (who seemed to be able to go about 10-11 hours between tablets) it helped, but wasn't entirely effective at controlling his headaches. One of the characteristics of SM seems to be that medication can be very individual - it can be a case of trial and error for a few months until you find the mix of drugs that helps your particular dog, and even then the mix may need to be tweaked from time to time as the disease progresses or (as in Oliver's case) a new drug is tried that works better for him.

Kate, Oliver and Aled

Brian M
20th September 2012, 10:57 AM
Hello Kate

Many thanks for replying on this as of course I am on a huge learning curve so its thanks to you and others that by replying to
my questions help me provide a better level of care for Daisy and also of course the superb staff at Chestergates where Daisy
attends every three months .I do appreciate every dog is different but its good to read other peoples experiances so thanks again
for your reply.

Rgds

Brian

Brian M
15th October 2012, 04:04 PM
Hi

I think Daisy seems to be scratching a tiny bit more so I phoned Chestergates and spoke to Ulreke and we agreed to up her Gabapentin 100 mg from
twice a day to three times which is in line with most on here ,we also go back for her three monthly visit on Nov 5 th and then we Simon in Feb which
is the big one I fear.

Waggles
15th October 2012, 07:13 PM
Good luck for the 5th Nov Brian and Daisy, will be thinking of you both.
Zoe

Brian M
15th October 2012, 08:04 PM
Hi Zoe

And good luck to all you down there .I normally stay with them till midnight but generally they are not too bothered unless its a huge bang which some lately seem to be but they all
seem to doze off as normal and leaving sitting there on my own .If I think back to some of the stupid stunts I got up to with my mates when was 14ish its a wonder I am still alive.

Brian M
18th October 2012, 03:06 PM
Hi
Just at work ,doing a bit for a change ,but again Cavaliers pop into my mind as always.!!! Question please -with Daisy now on three types of medication and with the two of us going to see Ulreke on 5 th November should I be asking to have her bloods checked ?

Thanks

Bri

MomObvious
18th October 2012, 06:28 PM
Hi
Just at work ,doing a bit for a change ,but again Cavaliers pop into my mind as always.!!! Question please -with Daisy now on three types of medication and with the two of us going to see Ulreke on 5 th November should I be asking to have her bloods checked ?

Thanks

Bri

Personally I think that is a good idea. I know with humans its always a good idea to have labs ran at least yearly when they are one ANY meds. My son takes ADHD meds and we have a complete physical with labs and EKG's every year. To me its a simple thing to ensure the meds are doing more good than harm.

Kate H
18th October 2012, 11:52 PM
If Daisy is on a diuretic such as frusemide or Zitac, Clare Rusbridge recommends regular blood checks, at least yearly. This is because a diuretic lowers the fluid level in the body as a whole, not just in the brain, and this can sometimes - usually after prolonged use - affect the kidneys. Your local vet can do this for you, and if there is any abnormality will consult with your neurologist (or perhaps I just have my vets well trained!).

Kate, Oliver and Aled

Karlin
19th October 2012, 12:04 AM
Agree, should be having at least yearly blood checks; I think Clare suggests every 6 months. Your vet can do this -- not generally done by the neurologist. I'd def do this now if you are seeing extra water drinking and let vet know she is drinking more than usual. If she is on a diuretic for her heart she will be drinking more but I haven't seen this with cimetidine.

Brian M
19th October 2012, 09:17 AM
Hello Karlin

I am worried now as she is drinking a lot more and stupid me did not put two and two together .If you can remember originally when she had her MRI with
Geoff S she was put on Frusemide but in the same week it was found Daisy had a Grade 1 murmur and her Cardio wasn't happy with her being on that diuretic so we took her off it and started her just on Zitac but we now know that in June her murmur had developed to a Grade 4 .I am wondering if I should try and see her Neuro earlier ie this Monday if I can and not Nov 5th or just go to my Vets tonight for bloods ,how long does it take for reasults to come through ? ,thoughts pls .

Rgds

Bri

Brian M
19th October 2012, 09:28 AM
Hi

I am too impatient and worried especially if it concerns any of my girls ,so I have phoned C/Gates and we see Ulreke at 5.00 pm tonight.

Karlin
19th October 2012, 10:17 AM
Wow you posted and 10 minutes later had an appt. :) I understand that. :lol: Probably not anything to worry about, I'd have just gone to the vet; generally only takes a day or so for results to come back. It may just be the omeporazole and cimetidine; don't know. Generally anytime there's a sudden increase in water drinking, it is good to visit the vet -- this can be the first sign of many conditions but also some dogs drink a lot more than others, and some meds will cause dogs to drink. The bloods are more just a monitoring regime when they are on meds (and reminds me that Leo needs them done). Let us know how the appt goes.

Brian M
19th October 2012, 11:06 AM
Hi Karlin

Its funny really as if it was anything wrong with me I would amble along to my Docs sometime in the next week or so but we all jump as high
as a kite when its our beloved Cavaliers ,these little dogs sure do get a tight grip of your heart .

Other better news this week is Monday we landed a job in Chester then Wed another one in Chorley and today one in Blackpool so from having one job
in Wolverhampton worth £300 ,000 we now have four with a total value of £1.5 mill with a good chance of another at Bangor Uni valued at another £Mill,so
all our lads we laid off earlier this year are coming back on Minday when two of the jobs start .And there was me dreaming of not working and having super
early morning walks on the seafront with the girls ,oh well back to chaos and mayhem again.

Karlin
19th October 2012, 11:12 AM
Great personal news, Brian! Long may it continue. :D

Brian M
19th October 2012, 09:16 PM
Hi

Home and they are all fed and now doing what Cavalier's excel at ie sleeping soundly. Upon examination Daisy exhibited more pain around her neck area coupled with a pronounced head tilt when she scratched but Ulreke was sure this pain was only temporary though it may last for a few weeks but she had observed it with one Cavalier for a period of six months .She advised me to stop the Omeprazole for a week and to observe her fluid intake and continue with the Zitac and Gabapentin and if no change to ring her and that then we will start giving Daisy an anti inflamatory Loxicom for a period of of two weeks only and then go back for a further review on the 9th Nov . I asked about the possibility of changeable air pressure with her SM and Ulreke commented maybe its a possibilty but there is no clinical evidence to support this .Daisy does not carry any excessive fluid and her MVD had not progreesed any since our last visit to Simon so that was a big relief for us .

Daisy's weight is better than I thought as I guessed at 8.75 - 9.00 and she is 8.25 Kilo so that is pleasing and apart from her known problems Daisy is still outwardly a happy girl with buckets of character and an outgoing personality with which while sitting in the waiting room she worked the audience as she can and played the poor drama queen for all she is worth , but that's my Daisy she adores an audience and uses all her vocal and physical charms to entertain them all .

We arrived home at 6.30 and the phone went shortly after, it was Ulreke advising that her bloods were fine, so I am happy as overall there was no bad news ,her weight is good her heart is as was ,the blood test was all done super quickly inhouse and that was fine and I knew within the hour ,but I am puzzled as to why Ulreke was so confident that the neck pain was only temporary so I shall ask a lot more in three weeks when we go back .

Sydneys Mom
19th October 2012, 09:55 PM
Glad it was good news. I can here how relieved you are.

Margaret C
20th October 2012, 04:13 PM
Daisy certainly keeps you on your toes. So pleased that overall she is doing okay.

Brian M
21st October 2012, 07:34 PM
Hi

We stopped her Omeprazole on Friday as instructed so Daisy has had her Gabapentin 3x100mg and her Zitac 3x50mg and nothing else ,we have had six fairly good walks and some of yesterday and
most of today I have been clearing up in the garden before Winter sets in .All of them have been with me ,apart from bedtime ,every minute and Daisy has not scratched once !!!!! I am very
pleased but totally confused .?????

Sydneys Mom
21st October 2012, 11:41 PM
Can't help with your confusion Brian, but glad Daisy is doing OK!

Brian M
29th October 2012, 08:11 PM
Hi

Question please ? With Daisy now taking three drugs till we go back for a review on the 7 Nov do I allow a time gap between them ,I allow an hour between the
Cimetidene and Gabapentin but when should I give her the Loxicom.?

Brian M
7th November 2012, 09:42 AM
Hi

Daisy and I go back to see her Neuro at 5.30 pm today ,she is currently on Cimetidene 50mg x 3 ,Gabapentin 100 mg x 3 and Loxicom 8 ml once a day .
How long should she be on Loxicom and as she is still scratching a bit any thoughts pls on how you think her Neuro might approach the problem now,I have
looked at CR alogarithm but cannot work out what direction Daisy should go .I like to have some knowledge and ideas to discuss with her Neuro rather
than sit there like and idiot saying nothing so help and thoughts please.

anniemac
7th November 2012, 02:45 PM
I like to have some knowledge and ideas to discuss with her Neuro rather
than sit there like and idiot saying nothing so help and thoughts please.

Brian,

I doubt you would ever look like an idiot because you do so much for your girls and continue to look for help etc.

I wish I could offer more help but since Ella is no longer with me and also from what I have read about Daisy's symptoms, they seem very different from Ella. It is so hard because each dog is different and it can be hard to find the right medication combination. I will say that once you do, it can make a big difference but of course sometimes that needs to change.

I know you said you have studied Dr. Rusbridge's treatment algorithm but have you thought about trying pregabalin (lyrica)? All I know is it really helped Ella but like I said, her symptoms seem different. The main difference I saw was she seemed like a different dog because light came back into her eyes. I am not sure if it was because gabapentin made her more tired or something else. I think you mentioned that she still is pretty active (I think) Ella also had issues with mobility (climbing stairs etc.) which I saw an improvement (and I don't think that is a problem with Daisy).

What I had wished I had done and that others have suggested, was to add or change one medication at a time so you can see what one was helping (or not) certain symptoms. I think I also started adding prednisone at the same time I switched to Lyrica (but she also took it sometimes befor) which may have contributied to the improvement with her mobility and not lyrica.

Ella was managed for sometime but eventually we added amantadine and she had tramadol. According to CR alogarithm, it says that if gabapentin is not showing improvements to try lyrica or/and amantadine and mentioned tramadol. Honestly, I am not sure if the amantadine helped her in the end but the tramadol did when she was in a lot of pain.

I really don't know what to ask and I am sorry. I just can share my experience and Ella did not have the head tilt that you mentioned.

I hope Daisy gets some relief and you find something to help her.

Brian M
7th November 2012, 04:13 PM
Hi Annie

I know you care and I am deeply grateful .I am just nervous about going down this road too quickly and then getting
to the end and having nothing left to turn to ,time seems to go much to fast but i of course will sit and listen and then
we will decide as of course I do trust her Neuro .

I will pick Daisy up from home at 5.00 put her in her harness on the front seat by me and then when I am driving down the
motorway M53 at 70 mph Daisy starts talking to me as she wants to sit on my knee but I dont think our police will enjoy
Daisy driving but she is a capable little girl .

I am off see you later and thanks .

Bri

Karlin
7th November 2012, 05:45 PM
Brian most of us with SM dogs would not be able to get rid of scratching entirely. All my SM dogs scratch to some degree. Adding in anything further or changing treatment depends on how much, how vigorous, is it distressing for the dog, whether that indicates an increase in other deficits that an owner or vet cannot see but a neurologist likely can. It is always useful to go in with a video or two. Sadly this disease almost always progresses and most of us will see the return of symptoms and must debate what that means and whether to change treatment. It is very wise to do this with a neurologist who can often see what we owners cannot. :flwr:

Of course if you are putting a dog in the front seat( not the safest place to be regardless, especially if only in a harness restraint) be sure to turn off the airbag -- an airbag would crush a small dog (which is why there are laws about putting babies and small children in front seats -- I think it is worth considering if a dog's life has the same value as a child's would, for any owner putting dogs up front. Most of us would say dogs are indeed deeply cherished by us -- and given they are the size of a baby and therefore at all the same fatality and serious injury risks, surely would always be safer in proper restraint in the back. :thmbsup:).

Let us know what your neuro says.

With mild scratching I sure would not be adding more to Daisy's treatment unless they see discomfort and other progression changes.

Tania
7th November 2012, 06:22 PM
I felt similar about switching from Gabapentin to Lyrica. I always thought of Lyrica as the last resort and I did not want to get there too soon. Coco recently had a serious crisis, her anal gland infection pushed her into heart failure and triggered acute sm pain. Until this time Coco never really displayed severe sm pain episodes, rarely scratched but would sometimes yelp. We switched her from Gabapentin to Lyrica , Coco is a completely different dogs, she is very playful and mischevious. I feel very guilty I did not do this sooner!
The problem is we do not know how much pain they are really suffering, I would imagine they learn to live with a lot, combined with wanting to please us and their high levels of serotonin we should try everything we can to make sure they are not suffering.

Brian M
7th November 2012, 08:57 PM
Hi

I know I am totally wrong in letting Daisy sit in the front but she and I know she is the boss and winds me around her little paw ,but that's our Cavaliers
but I promise no more driving for her .This is the harness we use for Rosie and Lily who are the two normally on the back seat while Poppy and Daisy go
in the crate in the back.
http://www.fleecedogharnesses.co.uk/car/bergan-dog-car-harness-review/?gclid=COmjydnVvbMCFSbMtAodpCcA5g.

We spoke about all the alternatives for Daisy who was scratching quite a lot in front of Ulreke and it was decided for the next two weeks, till we go back
on the 23 rd Nov, to reintroduce Omeprazole 10 mg x 1 and to keep her on the Cimetidene 50 mg x 3 and up her Gabapentin from 100 mg x 3 to 200 mg x 3
and take her off entirely the anti inflamatory Loxicom which seemed for Daisy to not help at all .If after two weeks there is no change it is likely then that
we will try Lyrica . I watch Daisy a lot and am still puzzled as I can see no physical sign of pain and she still outwardly displays exactly the same fun loving
look at me the centre of attention character she was and still is as when she was one or two ,she argues with Poppy for the title of boss Cavalier and wants
the toy that Rosie or Lily may have ,she has never ever screamed or acted or displayed any sign of pain and I wonder why ? I want to enjoy Daisy and
for her to enjoy herself so we will continue to go back to her Neuro as and when needed until this thing is under some form of control.
Thanks for your comments it does so help to share .The coffee machine has gone but then it hasn't worked for a bit .

MomObvious
8th November 2012, 01:19 AM
Brian I know you love your little Daisy to the moon and back :) Just wanted to send a little Virginia love your way:hug:It must be very hard to worry about Daisy so much, its just part of being the Daddy.

Oh and Daisy NO MORE driving....cute dogs and teenagers are the cause of much major accidents. At least in the US.

rubles
8th November 2012, 03:58 PM
Hi

We saw her neuro last night for a progress check ,I advised she is still scratches occasionally, but not a lot, and that her
medication of 2x100 mg Gabapentin from what I can see has not really made any great change to her scratching .I requested
a possible increase of the Gabapentin from 2 daily to 3 but her neuro wanted to include Omeprazole into her meds and of course
did not want to vary two meds at the same time so it was decided to proceed with the inclusion of the 10 mg of Omeprazole for
a three week trial then possibly increase the Gabapentin to 3x daily if needed .Her daily meds are now 3x50 mg Zitac ,2x100 mg
Gabapentin and 1x daily of 10 mg Omeprazole .I asked why would she take both the Zitac and Omep if they are both CSF reducers
and was advised that the Zitac acts as a fluid reducer and the Omep acts to try and reduce the production of spinal fluid ,am I right here or am I suffering from information overload . Any comments ,thoughts,advice or guidance most welcome please .

Daisy unfortunately has what was a small pimple on her left side which has now developed into a larger fibrous cyst/wart which I know has to be removed so I have arranged an appointment with a surgeon at C/Gates right after we see her neuro in three weeks time ,so tonight its off to my local Vets with Daisy to ask for a referral letter to them on the grounds that as she has a Grade 4 murmur I would like C/Gates to operate as they have a full time anaesthetist and a complete range of emergency equipment . My poor Daisy .:(

My Dawn's hospital appointment last Friday resulted in the endoscophy finding more ulcers some of which are still bleeding and with her
colonoscophy she found it to be too painful halfway through the procedure and told them to stop. So she has been summoned back to
see her consultant who wants her to have the colonoscophy again ,we go on .:(

What about a virtual colonscopy for Dawn?
I hope the new med regime will help Daisy.

Brian M
8th November 2012, 09:15 PM
Hi
Daisy is a lot better today hardly any scratching so thats good and this afternoon took Dawn to see her consultant a Mr Guy Pritchard he is happy
with her they found a cyst on the liver but not bothered with that and no sign of The Big C "hurrah" .She had to go for bloods to check her
iron levels and if they are ok she is discharged and to just go and see her GP .Been a good day .

anniemac
8th November 2012, 11:01 PM
Hi
Daisy is a lot better today hardly any scratching so thats good and this afternoon took Dawn to see her consultant a Mr Guy Pritchard he is happy
with her they found a cyst on the liver but not bothered with that and no sign of The Big C "hurrah" .She had to go for bloods to check her
iron levels and if they are ok she is discharged and to just go and see her GP .Been a good day .

I am glad Daisy is doing better but really happy to see Dawn's news.

Sabby
9th November 2012, 10:22 AM
So happy Dawn is ok and daisy is doing better.

Brian M
9th November 2012, 01:44 PM
Hi
Not a single scartch so far but we know we hope for a reduction not total elimination .I have done nothing but read and think about
Daisy's problem since Wednesday and came to the conclusion I need something else to think about rather than SM, so before I phoned
North West Surgeons and we see Mr Simon Swift at 10.15 am Tuesday 2 nd Jan 2013 now I can think and read about MVD in Cavaliers,oh well .


Also pondering about off camera flash contol between the Nikon SB 900 and the D 800 using a Pocket Wizard Mini TTI Transmitter and a Pocket
Wizard Flex TT5 Transceiver but all of it is totally baffling ,help ?????

Karlin
9th November 2012, 03:28 PM
Glad to hear Dawn is doing well and Daisy too -- :flwr:.

anniemac
9th November 2012, 05:31 PM
Hi
Not a single scartch so far but we know we hope for a reduction not total elimination .I have done nothing but read and think about
Daisy's problem since Wednesday and came to the conclusion I need something else to think about rather than SM, so before I phoned
North West Surgeons and we see Mr Simon Swift at 10.15 am Tuesday 2 nd Jan 2013 now I can think and read about MVD in Cavaliers,oh well .


Also pondering about off camera flash contol between the Nikon SB 900 and the D 800 using a Pocket Wizard Mini TTI Transmitter and a Pocket
Wizard Flex TT5 Transceiver but all of it is totally baffling ,help ?????

I know reading about SM can get consuming. I think you need to take the weekend with your girls, enjoy the day (hope it's not raining) and take lots of pictures. Your photos are always beautiful. You enjoy photography and I know you enjoy all your girls. Sometimes its nice to not think about those things, although important to know information, it's the days you spend enjoying them you cherish.

For a long time, I worried so much and tried to protect Ella from doing too much activity that she was missing out on things she loved. I'm so glad I finally realized this. I still had SM in the back of my mind but I found it was important to take a break to enjoy life. Those good days at the beach, when she chased after a bird, smiled are the memories that I have to remember her and it puts a smile on my face.

Kate H
9th November 2012, 09:26 PM
I'd second what Anne says, Brian. Yes, you need to be well-informed, but you have a neurologist and a cardiologist you trust, and they're the experts and there to help you. Take your girls for a long walk in Delamere Forest (don't lose Rosie in the fallen leaves - my ruby Oliver just disappears!), or to the North Wales coast, or along the estuary, and just enjoy them - whatever happens in the future, that's how you want to remember them.

So glad Dawn's news is good - we forget that tests can bring good news as well as bad.

Kate, Oliver and Aled

lindylou
9th November 2012, 09:31 PM
hi
pleased to read its good news for dawn and daisy improves with her scratching
sending kisses and cuddles to your beautiful girls

jasperpaw
10th November 2012, 09:05 AM
Great news about Dawn, hopefully she can now get on with her life, it must have been very hard for you all over the past few months and so pleased that Daisy is getting on well and not scratching so much.

team bella
10th November 2012, 07:21 PM
Great news about Dawn and Daisy, best wishes to you all x


Sent from my iPhone using Tapatalk

Waggles
11th November 2012, 04:45 PM
Great news for Daisy and Dawn. Such troubling times when the people (and dogs) we love the most are unwell - but always make sure you take time to celebrate the good news, no matter how small that might be.

Brian M
23rd November 2012, 03:14 PM
Hi

Off to see Ulreke with Daisy at 5.30 pm for a further review of medication ,am happy to leave her how she is .She still has the occasional scratch but not a lot .

Brian M
23rd November 2012, 09:45 PM
Hi
Will report tomorrow but has anyone used the drug Amitryptiline.

Brian M
24th November 2012, 07:53 PM
Hi

We saw Ulreke and spoke about Amitryptiline but after discussing its side effects especially with regards to the heart we quickly dismissed using it .We then went on to discuss
the benefit of Gabapentin and taking Daisy off it completely but decided to continue and it was then suggested introducing Pregabalin in its place but my concern here is that I
don t want to go down the road too far too quick and my thoughts since our last visit are that Daisy's condition is not that far advanced to consider introducing it yet ,by this time
Daisy after exploring all the offices decided to return and she seemed rather bored with events and so settled down by Ulreke and was soon snoring away .After more discussion
about the options open to us and after I advised that Daisy is off to see Simon on Jan 2nd it was agreed that we leave her meds as they are and reconvene on Dec 14 th ,bit
like David Cameron's meetings.

Daisy is still an outward determined little girl with her own individual sense of purpose ,on Thurs I had seven toy chews scattered about and Daisy had four ,Lily was not interested and
Rosie had one and Poppy had one but of course Daisy wanted above all else the one Poppy had so she went over to Poppy stood over her growling till a punch up started and I had to
quickly break it up and put all the chews away ,typical Daisy but thats how I want to keep her the loveable rascal she is.

As I type she has a grip of one of the toys and is busy humping away trying to make lots more little Daisy's for her Dad ,what a thoughtful little girl she is .

Brian M
11th December 2012, 10:13 AM
Hi
Back to Chestergates tomorrow for an update on Daisy's SM but I see no reason to change her meds but we will see what Ulreke says .We finish for Xmas shut down next Thurs 20 th and back on Wed 2nd Jan so I have booked Daisy to see Simon Swift on Friday 21 st 10.15 am for a complete heart check ECG,Echo and Doppler .She has now developed a slight cough so it might be Vetmedin I dont know this is another big learning curve ,but like all of us I will do everything I can to help her

Sabby
11th December 2012, 10:24 AM
Hi
Back to Chestergates tomorrow for an update on Daisy's SM but I see no reason to change her meds but we will see what Ulreke says .We finish for Xmas shut down next Thurs 20 th and back on Wed 2nd Jan so I have booked Daisy to see Simon Swift on Friday 21 st 10.15 am for a complete heart check ECG,Echo and Doppler .She has now developed a slight cough so it might be Vetmedin I dont know this is another big learning curve ,but like all of us I will do everything I can to help her

Hope everything is ok with Daisy and her heart is doing ok as well. Hopefully no need to go on any meds yet. I do feel for you and then you have got Dawn to worry about. You are lucky in a way that Chestergate is not far. If I want advice i have to email Clare and sometimes it takes ages so I just muddle through myself. My vet only knows what he has tead on Clares webside. Clare suggested that Rosie might go onto the drug trial. If it is Cambridge.Newmarket I might take all of them there for their SM.

You are in my thought.

Sabby
11th December 2012, 10:29 AM
Hi
Back to Chestergates tomorrow for an update on Daisy's SM but I see no reason to change her meds but we will see what Ulreke says .We finish for Xmas shut down next Thurs 20 th and back on Wed 2nd Jan so I have booked Daisy to see Simon Swift on Friday 21 st 10.15 am for a complete heart check ECG,Echo and Doppler .She has now developed a slight cough so it might be Vetmedin I dont know this is another big learning curve ,but like all of us I will do everything I can to help her

Hope everything is ok with Daisy and her heart is doing ok as well. Hopefully no need to go on any meds yet. I do feel for you and then you have got Dawn to worry about. You are lucky in a way that Chestergate is not far. If I want advice i have to email Clare and sometimes it takes ages so I just muddle through myself. My vet only knows what he has tead on Clares webside. Clare suggested that Rosie might go onto the drug trial. If it is Cambridge.Newmarket I might take all of them there for their SM.

You are in my thought.

Sydneys Mom
11th December 2012, 02:23 PM
Sending good thoughts for Daisy and Rosie.

Karlin
11th December 2012, 04:23 PM
Best of luck Brian on this visit.

Daisy isn't taking anything yet is she? If she has a cough she might be at the point or close to it for starting medications if it means her heart is beginning to struggle a bit on its own and not clearing fluid (maybe she has a mild cough from some other illness at the moment?). Simon Swift will know the right approach for her. :)

I am not sure I understand the earlier talk on gabapentin -- was there actually a serious consideration of removing Daisy from gabapentin and not giving her Lyrica as an alternative?Or was it only to take her off if she went on Lyrica? I assume the former?

Personally, I would not think of Lyrica s a 'last resort' or using up options -- it is a newer and more efficient version of the old gabapentin, basically and thus would for many many dogs be a better and more efficient drug which isn't needed in as large a dose or generally as many doses -- so is also easier to manage. I'd never think of moving to Lyrica as a case of running out of options if it gives a better response! -- and as others have said, many regret not moving their dog much earlier to Lyrica simply because it is a more effective drug for their particular dog's case of CM/SM. It's like deciding to suffer along on a lower dose painkiller like aspirin when there are many more effective drugs available. There are lots of options to add other drugs alongside Lyrica as well -- hardly a last option. I would really recommend trying it if gabapentin is giving a so-so response now. At the dose of gabapentin Daisy is at, she would pretty much be at her maximum for her size.

Also may I gently suggest that (from experience) I really think it's better not to focus on what might seem 'outward pain' and not mistake that perception as meaning a dog is or isn't "in pain" -- with Daisy, if she needs as high a dose of gabapentin as 200mg 3x -- what my Leo is on and the highest he can go -- then she has significant pain/discomfort of some kind causing her to need that level of neurological painkiller. Leo too is like Daisy in that he mostly just scratches, is very active and outwardly happy -- but I have grown used to seeing that he does have periods of greater discomfort and SM is clearly a burden and he has a significant syrinx now though it doesn't stop him running around or enjoying chews/toys/travel (having just come back from Yorkshire (Laverock Cottages for our third time :D )and 4-7 mile daily hikes!).

Scratching may not seem 'painful' as an outward response, but dogs are scratching for a reason. As humans say they most commonly experience terrible headache and intolerable skin-crawling sensations (which in my book would qualify as enormous discomfort and pain if I had to live with either) then I think it is hard to assume she is not experiencing pain or significant discomfort? Anyone with neuropathic pain will confirm the pain can be very difficult to tolerate yet not outwardly obvious or expressed and they just get on with life as they have to (there's good evidence with the dogs that they just grow to live with slowly increasing levels of pain too). I know Nicki amongst others -- as someone with significant neuropathic pain -- has said this so many times and the testimonial Tania posted from a Chiari sufferer also underlines this point. I'd aim for relieving her discomfort with whatever works best right now. I would not postpone for long, using something that could make her a lot more comfortable if it is an option, not least as none of us knows how much time our dog has left (as I know having one right now with both SM and MVD -- either could advance rapidly at any time). It would be distressing to find a dog might have done much better on a dfferent medication approach but not have used it because it was being "saved up" for a future that the dog ends up not having. :( I really advocate giving the best possible treatment as it is needed. :thmbsup:.

None of this is easy and it is hard to deal with both afflictions at the same time. :flwr:

Brian M
20th December 2012, 11:04 AM
Hi

Daisy goes back to see Simon tomorrow at 10.15 so fingers crossed she is still the same and not deteriorated in anyway .

Karlin
20th December 2012, 11:16 AM
Fingers and paws crossed!

Sydneys Mom
20th December 2012, 02:19 PM
Sending good thoughts and keeping everything crossed.

Brian M
21st December 2012, 02:05 PM
Hi

Dropped Daisy off and came away with a smile .Simon is a wonderful man the more I see him the more impressed I am ,his knowledge ,his attititude and his caring nature is 10/10 .Daisy is
still there I go back 1t 3.30 she is having her echo,electro,doppler and x rays as well but he is happy she has not entered CHF and there is really no change from last time in July .Her breathing rate is 14
a minute while 30 is the danger, number her heartbeat is about 95 but will know a lot more when I go back .He says the breathing rate is now considered the critical marker that points to poss CHF ,
I metioned her slight cough and he was not too concerned as a cough could be an indication of many things.She strolled into his room let him fuss over her and check her heart then promptly lie down
fell asleep and was snoring away .I shall post when I come back but what a wonderful day far far better than I expected .Rock On My Little Daisy .

RodRussell
21st December 2012, 02:14 PM
That's great news, all around, Brian. It is comforting that he is the one advising the cavalier club on MVD in the breed. Breaths per minute and comparing x-rays, as non-cutting edge as they may seem, are the "coin of the realm" as far as judging CHF these days. Dr. Mark Oyama has stated recently that even echos are not as important for diagnosing MVD as are the breaths and x-rays.

Brian M
21st December 2012, 08:30 PM
Hi
The day is over and it turned out far better than I thought .Simon in his report said "Daisy was bright and responsive though her heart disease has continued to progress although the
rate of progression is much slower .Although her heart is enlarged heart failure does not appear to be imminent .In dogs with heart enlargement the average time to heart failure was
about thirty months . Please continue with the low salt diet and Omega 3 fatty acid supplementation .I suggest we review in six months ."

Daisy is 6 next month so with a further 2 1/2 years before CHF then say a further 2 years on heart meds my fingers are crossed that she will be hanging on in at 10 1/2 years of age I HOPE.

Thanks All For Your Support

Brian

Sydneys Mom
21st December 2012, 08:47 PM
Daisy is 6 next month so with a further 2 1/2 years before CHF then say a further 2 years on heart meds my fingers are crossed that she will be hanging on in at 10 1/2 years of age I HOPE.

Brian

I HOPE too!

So glad you got a good report. That is really the very best Christmas gift!

ByFloSin
21st December 2012, 10:46 PM
So glad for you, and Daisy of course. I met and talked with Simon Swift once a couple of years ago and was very impressed. He seems a very caring and competent man, so I think you are right to have every confidence in him. 10 1/2 would be very good for our Daisy. Give her an extra hug from me please.

Karlin
21st December 2012, 11:43 PM
Glad the report was that she is doing pretty well and thanks to you and also Rod for the useful info on breaths/xrays... :)

Brian M
14th January 2013, 08:13 PM
Hi

" Daisy " is a star she has made my day again .We went her back to C/Gates for a further check up with ULrike at 5.30 tonight .Our normal routine is to sit on of the big sofa's and when Ulrike appears I take Daisy's lead off Daisy so Ulrike can watch her as she wanders after us or decides to meander off behind the reception desk, and when we finally reached the consultation room Ulrike said " What have you been doing to Daisy " my response nervously was why ,Ulrike replied " Daisy she seems so much brighter and better than last month she is more relaxed and panting nothing like as much as she was before .So a great evening appointment and we go back in three months for a further check and bloods .After a physical check all over she even said her neck pain had virtually disappeared .These little dogs of ours never cease to amaze .

Ps As I try and type while sitting on the bed madam has her favourite toy and is bouncing up and down like mad trying to make lots more little Daisy's for Dad and its bxxxxxx hard to type,the little horror

Karlin
14th January 2013, 10:28 PM
Great to hear that, Brian! :jmp:

karen baker
14th January 2013, 10:51 PM
Thats so lovely to hear that Daisy is making such good progress Brian, she sounds just like Sadie, bit of a flusey, except Sadie has,nt got a favourite toy, when she gets excited, she finds Ruby, you should see Rubys face, she gives that look as if to say....how common!!! lol Karen,Ruby and Sadie x

ByFloSin
14th January 2013, 11:31 PM
It's made my day to hear that Daisy is doing so well Brian. You can forgive them anything when they make progress like that can't you? Even shaking up the bed while you're trying to type. Well done Daisy and well done you Brian for taking such good care of her.

anniemac
14th January 2013, 11:44 PM
So glad Daisy is doing better!

Sydneys Mom
15th January 2013, 12:48 AM
So happy to hear this!
:jmp2::jmp2:

lindylou
15th January 2013, 01:01 PM
hi brian
i'm so happy to hear daisy's is doing great and hope she is with you in many years to come
its all down to you brian love care affection