It must be really sad having so say goodbye. I am on the other side of the fence, having taken in our Sonny who is an x-stud. He adapted to our household really fast and now I could not imageine life without him, and I think he can't imagine life without us. I hope Isis will have a wonderful & full life with her new humans.
I know exactly how you feel Bruce, I placed my very much adored Darcy in a new home last week-end and it tore me apart to do it, happily he too is doing just great in his new home as your Isis is in hers.
Bruce's warning is very true folks, there is much heartbreak involved in dog breeding, loads of happy times, but also an incredible amount of tough decisions too!
Am very happy to hear Isis is well settled in her new home, and you know as well as I do that you have done the right thing by her in making this incredibly tough decision! A huge :hug: to you Bruce :hug: