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We did not do any tissue samples as my vet is small and I would have had to let the body go-this I could not do as I was not prepared to lose her so suddenly. Anyway, the necrospy was inconclusive and the vet suggested it was heart attack or stroke.
One thing that now comes to mind with Sunshine and Jenny is that there is a heart condition -- Nicki knows more -- that can affect cavaliers and cause a sudden 'blow out' of the heart valve, typically around age 3-4, with no advance warning. A dog that had just come into my rescue died of this about three years ago -- he and another came in from a breeder who was rehoming some dogs. He basically was in the vets at the time and his heart just failed -- very unusual for a young dog like this. Nicki and a breeder friend were aware of this issue in the past with some cavaliers. It isn't common and there's really nothing that can be done about it -- the valve just goes when they get around that age.