SO sorry to hear this yes definitely sounds like an SM episode. You were really clever to write down what happened that's very helpful to the neuros and vets.
Tramadol is generally used for Palliative care as it has very mixed results and doesn't always work for very long. Glasgow prescribed it for Teddy in that way.
Do hope that the increased dose will help Misty, the sudden change in the weather hasn't been helping.
I know many people who use Tramadol for their dogs, and have never heard one of them mention it affecting their dog with a 'doped up' scenario.
I'm so sorry she is experiencing so many issues now. Hugs to you.
I noticed on your posting that your dog is receiving 150 mgs of Gabapentin three times a day. Does mgs = mils. My Charlie is taking 0.60 mils twice a day.
Meanwhile I hope Misty is feeling better.
Originally Posted by murphy's mum
the last time Ruby had a serious episode with yelping and screaming she lost the ability to jump for a couple of days. It does sound as though it is related to the SM. Its fairly normal Im led to beleive that these one off episodes occur.
When I took Ruby in after the above episode (it led to outbursts of screaming for a while that lasted a very long time- she was extrememly distressed) to see Clare she said that it has no bearing on whether her consition has deteriorated- its an outburst that on its own doesnt really tell us much apart from than at that momment she was in alot of pain.
I hope she is feeling better- Clare told me that if it does happen she can have an extra dose of her Pregabalin (although not if with in 3 hrs of the last) and Metacam- she offered a prescription for Tramadol but I declined on the advise that it is quite addictive and once on it, it can be hard to get them off again.
Im happy to say she hasnt had an episode since then to that extreme and that was just over 15 months ago!
I don't have any experience of a yelping episode, but about 7 years ago (before he was diagnosed with CM/SM) Oliver suddenly lost the use of his back legs - they kept collapsing under him. This lasted about 2 hours and then he was fine again. The vet thought he might have had a small seizure, but in retrospect I would guess it could have been CM/SM related. He's never had a similar episode, although now at age 10.5 his back legs are a bit wobbly but still perfectly usable on the flat, and this is almost definitely SM related. Short of some kind of mobile scanning device that dogs can carry around with them(!), we can't know exactly what happens all the time with this disease that interferes with the nervous system - except that these sudden one-off episodes seem to occur with a number of dogs. Scary - but may never happen again.
Kate, Oliver and Aled
I don't think so mgs is milligrams. Misty is on capsules which I split so she can get 150mgs a day :)
Originally Posted by rubles
She hasn't done it again I'm please to say, but is still scratching, but not as much. We'll see how she goes, I'm hopeful the increase in the Gabapentin is doing the trick.
Kate Misty's back legs aren't great either, she's never been able to jump into the car, while Murphy flies in. She's also hesitant to jump off of things too, like the couch or the bed. If she's having a bad day, she takes the stairs one at a time. It's been snowing here today too, and I notice she drags her back left foot at time, as it was three paws and a line in the snow while she was trotting.
Sandra, in the UK we are not able to obtain the liquid form of Gabapentin - I have been told that this is because it is very irritating to the gut lining so they do not recommend it.
Originally Posted by rubles
From Formulation in Pharmacy Practice 2nd Edition
Gabapentin 250mg per 5mL so 0.6mls would be a minute dose - there should be information on the label or leaflet with your Gabapentin to confirm the formulation.
I took another look at the label and this is what it says
Give 0.62 mL orally every 12 hours. \The bottle contained 100 mg/mL oral liquid.
when checked things out with pharnacist (human variety) he said the human grade syrup contains something toxic to dogs. Charlie's came from the local vet college.
Originally Posted by Nicki
Sorry I missed this.
so Charlie is only taking 62mg twice daily? How much does he weigh? That still sounds like a really small dose.Is it controlling his symptoms?
Clare Rusbridge's recommendation is 10-20mg/kg 2-3 times daily. Kayleigh at 7.5kg started off on 100mg twice daily and then three times daily - so daily total 200 to 300mg - she's currently taking 450mg.
You can obtain blood tests to check the therapeutic level of the drug in the blood stream