lady's in heat at the moment we seem to have gone back to when she was much younger we take her out more often and that stopped any accidents in the house. She makes a little whine and goes to the door when she needs to go out which helps. Which we both praise heavily (saves me getting any poochie bells!)
When she first went into heat she did wet her crate once which she's never done before. I think it must be all the hormones they forget their potty training. But if your concerned then ring your vets i am sure they wouldn't mind talking over your concerns much better to be safe than sorry.
Natalie, mummy to lady (blen) 8 months old