Curly Coat -- Rough Coat Syndrome in Cavalier King Charles Spaniels
A rarer but far more severe form of dry eye syndrome in some Cavalier puppies is a combination of dry eye and a congenital skin condition called "curly coat" or "rough coat" syndrome (ichthyosis keratoconjunctivitis sicca). The reference to a curly or rough coat comes from the unusually curly abnormality of the Cavalier's coat which is apparent at birth. However, the puppy also suffers from an extreme version of dry eye, and as the affected dog matures, it develops a deterioration of the skin which results in seborrhea, consisting of skin inflammation and excessive oiliness. Also, the dog's teeth, gums, and other connective tissues may be adversely affected. The form of dry eye associated with curly coat also is rare in that it is of congenital origin.
In cases of curly coat (rough coat) syndrome, nearly continuous daily care, including very frequent medicinal bathing, is required to treat the skin condition, as well as applying the eye medications. In a 2003 study reported by Dr. Keith C. Barnett, OBE MA PhD BSc DVOphthal FRCVS DIpECVO, European Specialist in Veterinary Ophthalmology, the dry eye condition of curly coat dogs may be so severe that cyclosporine therapy is ineffective, and the skin condition progresses into severe lesions. In a September 2006 paper, Dr. Barnett reported that successful treatment of the skin condition is not possible, although there can be some improvement in the dry eye condition.
Dr. Barnett reported that the need for constant care of the eyes and skin may lead breeders to resort to early euthanasia of the affected puppies as the only humane result, to avoid the dogs suffering from lifetimes of extreme discomfort and permanent eye damage.
No cases of the combination of dry eye syndrome and curly coat syndrome have been reported in any other breed. Studies have been conducted in the United States, United Kingdom, Australia, Sweden, the Czech Republic, and Iceland. It is believed to be due to a simple autosomal recessive gene. If so, then affected puppies are more likely to be found in cases of line breeding or inbreeding on carrier bloodlines. During a two year period recently in Iceland, more than half of many litters of Cavalier puppies were born affected by the syndrome. The disorder may be more widespread than previously believed as more owners and veterinarians become aware of its symptoms.
Good God, Ivomec should NOT be used on dogs or cats, it's a cattle/sheep wormer and could actually kill a dog or cat. It CAN be used on rabbits in very small doses ( I use it on my bunnies, it's prescribed by my vet for them) but should never ever be used on dogs or cats. It's no wonder the poor dog has such bad skin, the ivomec has probably made it a hundred times worse.
Some people are just so stupid aren't they.
Hope the poor doggy recovers well now that it is in good hands. I take it the farmers won't be having it back? I certainly hope not.
Alison
Don't use Ivomec as heartworm preventative for dogs
Ivermectin is the active ingredient in Heartgard, a prescription heartworm preventative for dogs. It is also the ingredient in Ivomec, a large animal wormer available at feed stores over the counter.
This has led some people to try to save money on the purchase price, and to avoid paying for heartworm testing, by purchasing the large animal Ivomec for their dogs. There are three reasons why this is a bad idea.
1. This practice is the number one cause of ivermectin toxicity in dogs**. This is because Ivomec is much, much more concentrated than Heartgard. Even if you are trained in administering medicine, it is very easy to give your dog too much. Think how you would feel if you poisoned your dog trying to save a buck.
2. Federal law* prohibits vets from telling you to use Ivomec this way. This means, you are probably not getting annual HW testing done on your dog--and annual testing is a good idea, because no preventative is perfect, especially when imperfect (read: human) pet owners are administering it.
3. Heartgard comes with a warranty. If you are getting Heartgard from your vet, and you are annually testing, the manufacturer will pay for the costs of treatment if your dog develops heartworm (as of the time of this writing). There is no such warranty on Ivomec.
*AMDUCA, the Animal Medical Drug Use Clarification Act. This is a widely misunderstood law, even by vets, but it prohibits veterinarians from using an off label drug when the active ingredient already exists in a labelled drug for that purpose in that species. It's not widely enforced in small animal medicine, but it is federal law, nonetheless.
**Information obtained from the American Association of Veterinary Toxicologists.
(I am not a licensed veterinarian. I possess an Associate of Applied Science degree in Veterinary Technology)