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Thread: Question about gabapentin

  1. #1
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    Default Question about gabapentin

    Hi...I haven't posted here in quite some time. Lily, my 3 year old, was just recently diagnosed at Auburn University Vet School here in Alabama with SM with a very small syrinx, but with moderate symptoms, and PSOM. The neurologist said she was borderline for surgery, so we have opted to treat her with medication at this time. She is on 50 mg gabapentin twice a day, and 1/2 prilosec 2 times per day. There is been a tremendous improvement in her symptoms since we started the medication. I have noticed that about mid afternoon when her morning dose of gabapentin is wearing off, she begins to face rub and scratch. I asked the Dr. at Auburn about increasing her medication to 3 times per day. She said they like to give the lowest dose possible, and because she will be on the medication for the rest of her life, they would prefer not to increase the dose unless her symptoms worsen. My question is, for anyone giving gabapentin 3 times per day, did you increase the dose, or did your nuero? What would it hurt if I increased to 3 times per day? Would you do this without your nuero's recommendation? Also, is it difficult for you to get gabapentin in your area? I had to have it compounded, at a compounding pharmacy because it does not come in a 50 mg dose. It was pretty pricey. What are you paying where you live?

    Any info would be apprecited.
    Last edited by Shay; 9th October 2009 at 03:23 AM. Reason: Signature won't save
    Sharon,
    Mom to Bleinham Cavaliers Lily, 5 years old, and Alfie, 8 year old puppy mill rescue.
    At the Bridge, Chloe, Lhasa Apso.

  2. #2
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    Shay I'm assuming your neurologist is Dr. Shores at Auburn. Abbey had decompression surgery by him last march. She also was on the liquid form and it is pricey. After a couple bottles of it I asked if I could up her to the 100 mg capsules and I get them at Costco for practically nothing. Abbey was on 75 mg when I asked him so she was on a higher dose than your baby.
    Linda, Georgia, USA
    Winston--shih tzu-male, Darby female tri, Bentley male blenheim and Chelsea, black-tan
    Abbey my beloved tri who is so embedded in my heart--RIP Sweet Princess

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    Sharon:

    I just had a brainstorm and I know you. lol. We spoke on the phone. geesh I guess I was in lala land when I wrote that yesterday.

    When we were having it compounded Sharon I believe it was around 75 bucks.
    Linda, Georgia, USA
    Winston--shih tzu-male, Darby female tri, Bentley male blenheim and Chelsea, black-tan
    Abbey my beloved tri who is so embedded in my heart--RIP Sweet Princess

  4. #4
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    I get gabapentin 100mg capsules at Costco.com for less than $20 for 200 capsules. I was paying more than twice that amount at drugstore.com until I priced it at Costco.

    Jeszel was on 100mg 3x per day, but still had a scratching episode once or twice a day, so my neuologist raised it to 200mg 3x per day. I have not noticed any significant improvement with the increase, but left it at 200mg. My neuologist said that we can raise it 300mg, but that is the max. I decided to leave it at 200mg so that I have room to raise it later if it becomes less effective.

    I hope that Lyrica will get less expensive some day soon, so that I could afford to try that, but it may takes years to get a generic for that drug.

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    I personally wouldn't raise the dosage until you talk to her neuro. This is something that probably could be handled over the phone though. 50 mg/twice a day is a pretty low dose of gabapentin. My Riley has SM but is not on gabapentin. She had decompression surgery last year and was on 100mg/three times a day for about three months after surgery, but we took her off since pain and scratching were not issues for her. Ithink that the effects of the gabapentin wear off pretty close to 8 hours after the last dose, which is why you're probably noticing that she's uncomfortable. I would think that at the least she should be on a three times a day dosing schedule. So, I would call your neuro back and ask about increasing the dosing schedule. There are many dogs on this forum who have been on a much higher dose of gabapentin for quite a while (years).
    Bev
    Oliver (blenheim, born 3/2001), Riley (black & tan, born 8/2002,), Madison (ruby, born 9/2003), and Oz (tri-color, born 7/2007)

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    Best to call the neuro first. It will need to be explained to you what to look out for if your dog can't tolerate that higher dose, that's what happened to us. Some neuros are happy to discuss things over the phone. Also your vets may expect the neuro to contact them notifying them of the increase.
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    Sharon I e-mail Dr. Shores alot and he replies usually within a day. If you need his e-mail addy just e-mail me and I'll give it to you. Like I told you I asked him before I upped Abbey's dosage so I agree with the others about that.
    Linda, Georgia, USA
    Winston--shih tzu-male, Darby female tri, Bentley male blenheim and Chelsea, black-tan
    Abbey my beloved tri who is so embedded in my heart--RIP Sweet Princess

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    Thanks all for the replies. I did call the neuro before I posted this, well actually his assistant, who is the resident student on her case. She is the one who told me that they want her on the lowest dose possible, if or until her symptoms worsen. They are calling her case mild SM, but with moderate symptoms. The reason I was asking is because I know that most dogs I have read about are on a greater dose. It could also be the PSOM that is causing similar symptoms, which of course the gabapentin won't relieve. She is so much better with the medication, and I am grateful for that.

    Hi Linda.....I talked to. Dr Akin not Dr. Shore. I will call him next time, if she continues scratching after her morning dose wears off. I may just have my Vet call him, because he would have to write a new script if we increase to 3 times per day. My regular Vet only wrote the script for 3 months, so we will need to talk to Dr.Shore when it's time to re-fill. How is Abby? Hope you are both doing well.
    Sharon,
    Mom to Bleinham Cavaliers Lily, 5 years old, and Alfie, 8 year old puppy mill rescue.
    At the Bridge, Chloe, Lhasa Apso.

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    That's a low dose -- generally the recommendation is trial for two weeks, and if the dog starts to have symptoms within the time of a dose, to increase the dose or frequency (in your case I'd quess the frequency before the dose).

    I'd split capsules rather than compound -- that's what I did when Leo was on your dose. Leo is now on 150mg 3x so I get the 600mg tablets (as in this size you can avoid the capsules) and use a pill cutter to split in 4. The shape wouldn't suit cutting into 12 pieces though.
    Karlin
    Cavaliers: Jaspar Lily Tansy Libby Mindy
    In memory: Lucy Leo
    Cavalier SM Information site:www.smcavaliers.com

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    Ruby started on Gabapentin 3 x daily 100mg but she was quite painful at the time. After 4 months and still seeing scratching/rubbing episodes and she was wobbly on her feet also we transitioned in to Pregabalin.
    She is now on 50mg 2 x daily and she hasnt scratched once or rubbed her head once in the 2 weeks she has been solely on it. She is much steadier on her feet now as well.

    Karen

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