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Thread: DOG WORLD and APGAW REPORT

  1. #11
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    Default Dog World and APGAW REPORT

    Could I go back to this subject .

    The CKCS Breed Standard clearly states that the Stop in Cavaliers should be Shallow.

    For many of to-day's Cavaliers they have a Deep Stop.

    The APGAW Report mentions that Cavaliers have Brains too Large for their Skulls.

    Has this come about because of the alteration in to-days Cavaliers in having a Deep Stop.

    Also could I mention that ,

    If two Carriers are Mated of a Disease,SM, MVD ,statiscally,

    50% of the Litter will be Carriers.

    25% of the Litter will be Affected .

    25% of the Litter will be OK.

    Surely the only answer for our Cavalier Breed ,since it's not known the Genes for CM/SM, and MVD, is for Cavalier Breeders to MRI Scan ,and Heart Test their Cavalier Breeding Stock.

    What other way is there to go, if the Cavalier Breed is to be saved.

    At the moment it is a Sick Breed, .Nobody can deny this fact.
    Bet (Hargreaves)

  2. #12
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    Also could I mention that ,

    If two Carriers are Mated of a Disease,SM, MVD ,statiscally,

    50% of the Litter will be Carriers.

    25% of the Litter will be Affected .

    25% of the Litter will be OK.
    Bet, this in not correct. It is really important to understand that the mode of inheritance relates to the individual, not the group as a whole. Each pairing of egg and sperm is an individual event.

    For a single recessive gene mode of inheritance, if both parents carry one recessive and one dominant gene, each puppy has the following:

    25% chance of not receiving the recessive gene from either parent;

    50% chance of receiving one recessive gene from one parent;

    25% chance of receiving both recessive genes from both parents.

    This difference is huge. In this situation, it is quite possible that all the puppies in a litter could receive both affected genes and or that none could. (The same holds true for the sex of a puppy. Each puppy has a 50/50 chance of being male or female. That doesn't mean that 1/2 the puppies in each litter will be male and half will be female.)

    Looking at the variability of symptoms and age of onset of SM, it wouldn't surprise me at all if there were several "types" of SM, each caused by different genes and/or gene combinations. Research is crucial to finding the answers.

    J.
    Last edited by Jay; 11th November 2009 at 06:40 PM. Reason: clarification
    J. and pups, Gem, Monty, Harley and Sapphire

  3. #13
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    Default Dog World and APGAW Report.

    This Information was given in OUR DOGS to-day.

    There is an excellant Article in Dogs Today written by Jemima Harrison,just published,she mentions ,DNA Testing is a Modern Miracle,but there can be Negative Effects to Playing God With Genes.

    She mentions ,that the most that can be hoped for to reduce Problems to an acceptible level ,and DNA Testing ,while a wonderful Tool ,will only ever be Part of the Answer.

    She also mentions the EBV Scheme,this Article is well worth a Read,
    Bet (Hargreaves)

  4. #14
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    Quote Originally Posted by Bet View Post
    This Information was given in OUR DOGS to-day.

    There is an excellant Article in Dogs Today written by Jemima Harrison,just published,she mentions ,DNA Testing is a Modern Miracle,but there can be Negative Effects to Playing God With Genes.

    She mentions ,that the most that can be hoped for to reduce Problems to an acceptible level ,and DNA Testing ,while a wonderful Tool ,will only ever be Part of the Answer.

    She also mentions the EBV Scheme,this Article is well worth a Read,
    Jemima Harrison is a writer, director and editor-- I didn't know she was a renown geneticist.

  5. #15
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    Default DOG WORLD and APGAW Report.

    Jemima Harrison is not claiming to be a Geneticist,she has been in touch with other Geneticists,

    Dr B Cattanach,
    Dr Jeff Sampson,
    Dr Cathryn Mellersh,
    Biologist ,John Burchard

    Put their information into this Article.
    Bet (Hargreaves)

  6. #16
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    There is an excellant Article in Dogs Today written by Jemima Harrison,just published,she mentions ,DNA Testing is a Modern Miracle,but there can be Negative Effects to Playing God With Genes.
    Bet, is there a link to this article?

    J.
    J. and pups, Gem, Monty, Harley and Sapphire

  7. #17
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    Quote Originally Posted by Bet View Post
    Jemima Harrison is not claiming to be a Geneticist,she has been in touch with other Geneticists,

    Dr B Cattanach,
    Dr Jeff Sampson,
    Dr Cathryn Mellersh,
    Biologist ,John Burchard

    Put their information into this Article.
    I have been in touch with other BOARD CERTIFIED Cardiologists -- yet that falls on deaf ears.

    You didn't give us any way to see the information-- Just blurted what Jemima said.

  8. #18
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    Default Dog World and APGAW Report

    Jay ,do you mean the mention of the Carriers, just do OUR DOGS ,it was in their Forum to- day.

    Jemima Harrison's article, was in the Dogs Today magazine I received to-day ,just do up Dogs Today.and you should get it.
    Bet (Hargreaves)

  9. #19
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    Quote Originally Posted by WoodHaven View Post
    ...You didn't give us any way to see the information-- Just blurted what Jemima said.
    Sandy, if you want to know what the Dog's Today article says, why don't you just read the article, rather than pick apart Bet's notice that the article exists?

  10. #20
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    Quote Originally Posted by RodRussell View Post
    Sandy, if you want to know what the Dog World article says, why don't you just read the article, rather than pick apart Bet's notice that the article exists?
    I didn't pick apart anything. She stated Jemima said-- I looked for the information -- didn't see any references to any persons with Doctorates.

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