Oh Becky! Unfortunately, we have all had to have this conversation too much!! I had this happen about a month ago with a woman who had the audacity to tell me that SM was not in Australia because we have quarantine. Oye. But good for you for bringing up the topic and putting it out there. Every mouth that opens and every person that just tells one more person, is a great benefit to awareness about this disease. It may have fell on deaf ears (I know mine have), but I always hope one day, someday, it will sink into their gray matter and maybe they will google it. Maybe they will ask their vet. Maybe the will ask someone else. Who knows, but you did your part, good job.
I am with Kate on this one (and I hate to be cynical, but I am), I would be very wary of having them play until Toby gets fixed...especially not off leash! It won't be that long to wait anyway and you could actually make it not an awkward convo by just saying..."I would love them to play, Toby will be fixed in "x months" and it would be great to hang out then...maybe we can exchange numbers?" you could then go on to maybe even breech the subject again of "oh, I am just a member of a Cavalier organization that focuses on the health and future of the breed, and knowing so much about syringomyelia and inherited genetic diseases in the breed, I just need to be responsible that Toby is not around intact females until he is desexed as I would be crushed if I ever contributed to this disease since Toby has not been MRI cleared" NOW, I know that puts it more back on you, which I did on purpose because then it almost talks about the issue from Toby's side (even though it is so HER issue so don't think I am glossing over that!!), but it makes it less threatening and more open if we talk about it from our side vs. thiers you know? Same as a relationship argument, ha ha. It might actually get her thinking since you are serious enough to not even let your dogs play together til Toby is desexed, that this must be a pretty serious thing to you.
That might work. I would really be wary of play time before desexing since her intentions were breeding first off the pitch. But after Toby is desexed, maybe you guys can have some play dates, maybe you will get along, maybe the conversation will be about cavs a lot and you guys can have friendly discussions about all of this (health, breeding etc.). It sounds like she actually does not know a lot vs. knowing and doing it anyways, so maybe some gentle, friendly education is in order. That actually might be your gift of friendship to her, who knows. You can't blame people who don't know, you can just try to educate them

(though, you can blame people who are educated and just close their ears!!).
Cute little Toby, he seems to already have the first few chapters written of a very adventurous book!

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