16th July 2012, 02:43 PM
No connection between Chiari-like malformation and epilepsy in cavaliers
In a 2012 report in the Veterinary Journal, UK neurology researchers C.J. Driver, K. Chandler, G. Walmsley, N. Shihab, and H.A. Volk examined the MRIs of 85 cavalier King Charles spaniels, looking for a relationship between Chiari-like malformation (CM), ventriculomegaly, and seizures in the dogs. The 85 CKCSs all had CM; 27 of them also had had seizures. They found no association between CM, ventriculomegaly, and the seizures. The seizures were classified as having partial onset -- meaning that they occur in in one area of the brain, unlike generalized seizures which typically affect nerve cells throughout the brain -- in 61% of the dogs. They also stated that "Another cause of recurrent seizures in CKCS (such as familial epilepsy) is suspected, as previously reported."
More details at http://cavalierhealth.org/epilepsy.h...iation_between
17th July 2012, 11:19 AM
Thank you for posting this Rod, it's good to have this finally clarified. We often hear of CM/SM dogs with epilepsy too. Sadly it appears to be just that both conditions are prevalent in the breed I have had one severe SM dog with epilepsy who was PTS due to the epilepsy.