Results 1 to 3 of 3

Thread: omeprazole and cimetidine

  1. #1
    Join Date
    Jan 2012
    Location
    Ontario
    Posts
    100
    Post Thanks / Like

    Question omeprazole and cimetidine

    The algorithm (sp) on C. Rusbridge's website refers to those two drugs so I Googled to see what they are used for and found they are for stomach acid. What is the connection with SM and neurological pain?

  2. #2
    Join Date
    May 2006
    Location
    Orlando, Florida USA
    Posts
    1,240
    Post Thanks / Like
    Blog Entries
    1

    Default

    Quote Originally Posted by rubles View Post
    The algorithm (sp) on C. Rusbridge's website refers to those two drugs so I Googled to see what they are used for and found they are for stomach acid. What is the connection with SM and neurological pain?
    This is from http://cavalierhealth.org/syringomyelia.htm#--_drugs

    Drugs which reduce the production of cerebrospinal fluid, including proton pump inhibitors such as omeprazole (Prilosec, Losec, Omesec, Zegerid), and the diuretics, furosemide (Lasix, Diuride, Frudix, Frusemide) and spironolactone (Aldactone), are reported to be useful to reduce intracranial pressure. Long term use of omeprazole is not recommended by some neurologists, as its long term use reportedly has increased the risk of stomach cancer in lab rats. Short term use reportedly can cause a "profound and sustained increase in serum gastrin concentration in dogs." See June 2011 report.

    Cimetidine (Tagamet, Zitac), which is a histamine H2-receptor antagonist -- an antihistamine. Histamine contributes to inflammation and causes smooth muscles to constrict. Cimetidine is diffused into the cerebrospinal fluid and reportedly may contribute to reducing the flow of CSF. When taken with gabapentin, cimetidine also reportedly may increase the amount of gabapentin in the blood by decreasing its elimination. Therefore, when taken together, the dosages may require adjustment.
    Rod Russell

  3. #3
    Join Date
    Jan 2012
    Location
    Ontario
    Posts
    100
    Post Thanks / Like

    Default

    Thanks Rod
    I've got a lot to learn.
    Sandra

Bookmarks

Posting Permissions

  • You may not post new threads
  • You may not post replies
  • You may not post attachments
  • You may not edit your posts
  •