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Thread: Omeprazole dosing solution

  1. #1
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    Question Omeprazole dosing solution

    Charlie has been put on omeprazole along with gabapentin. The omeprazole is mixed in a suspension by the chemist and is pricey. He takes 2.5 ML (5MG) per day and is cost prohibited for long-term use. Charlie is responding favourably and I'd like to keep him on it. It is available over the counter in 2.5 MK packets that are mixed in water for humans.
    So has anyone had experience mixing ths drug for their Cavs?
    If not how is this drug administered?

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    Hi rubles
    My Daisy is on the same meds plus Zitac .August 2011 she went on Zitac 50 mg three times a day which didn't seem to me to benefit her from what I could see
    then this June her Neuro added in Gabapentin 100 mg twice daily and again to me it seemed to have no effect on her then August we added in Omeprazole 10 mg
    and bingo hardly any scartching at all .We go back early Nov and her Neuro may take her off Zitac but as this and her Omeprazole work in diffferent ways ie one
    lessens production of CSF and other controls amount of CSF already produced I don't know what she will advise .

    I have taken a photo of her Gabapentin and the Omeprazole that she takes and as you see the Omeprazole is only a small tablet ,both are given wrapped in a tiny
    bit of cheese to tempt Daisy so she has no trouble taking either .

    My wife Dawn has been having some medical problems recently and one of her meds is Omeprazole 20 mg and apart from the amount of med in each they both seem
    identical in the drug compounds used so I can't see any reason why the human variety you suggest can't be given .When my girls are given any meds not yet tested and
    passed for animal use the doggy hospital always give me a verbal warning about this together with an info sheet about that particular drug .

    Hope of some help ,there are many here with far greater knowledge than I so if any of my comments are incorrect I am sure someone will be one very shortly to correct
    anything that is wrong .My best wishes to you and Charlie in dealing with this terrible thing though with my Daisy she also has a Grade 4 murmur which I consider that to
    be her biggest challenge by far ,but I must also say that neither problem so far seems to have any effect on her zest for life so she is still the same mischevious Daisy she
    was when a pup .

    [IMG] Gabapentin 100 mg and Omeprazole 10 mg by brianmurtagh49, on Flickr[/IMG]
    Brian M

    Poppy the Tri, Daisy the Blen, Rosie the Ruby and Lily the B & T

  3. #3
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    If you were to use the one that gets mixed in water, you could put it in a syringe and gently swish it into Charlie's mouth. I give Bosco Lyrica, which my vet can't get at the moment, so I've been buying it from my pharmacy - same drug as humans get. It seems vets are low in the pecking order when there is a shortage of drugs
    Shirley
    A comfy lap for
    Trapper - tri boy Feb 2004, Bosco - ruby boy Jan 2008

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    Brian
    Thank you for posting the pictures of the two medications. They're both helpful.
    Omeprazole requires a prescription. Ranitidine (cimitidine over the counter) comes in the size I need. The vet learned about Omeprazole and cimitidine via this site and Clare Rusbridge's website. The Ontario Veterinary College didn't prescribe them to Charlie either so they're off label use my vet isn't knowledgeable about. She's very co-operative and open to suggestions and did prescribe the Omeprazole. So if the ranitidine is similar ................
    The amount precribed is vastly different too. Is your wife's Omeprazole available over the counter without prescription?
    Charlie has 0.7 millilitres of Gabapentin every 8 hours--a fraction of Daisy's dose. The Gabapentin capsule comes in 100 and the chemist mixes it in a suspension lasting about a month and a half to prescribe the smaller amount. That amount is hard to understand when compared to what Daisy successfully takes.
    I'm glad Daisy and wife are doing well. How old was Daisy when SM diagnosed?
    Thanks again for all your help.

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    Hi Rubles
    My wife get her med thru her doctor and I get Daisy's through our vet .Daisy only takes 1 @ 10 mg daily so if your Charlie is n 5.6 mg every 8 hours or 16,8 mg every 24
    hours he is on much more.

    Bri
    Brian M

    Poppy the Tri, Daisy the Blen, Rosie the Ruby and Lily the B & T

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    Hi Brian,
    I didn't write that very well.
    Charlie has 2.5 ml/5mg of omprozole once a day
    and 0.7 millilitres of gabapentin three times a day.
    I get really confused with the measurements.

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    My Oliver doesn't have omiprozole, but giving it as a suspension seems to me unnecessarily complicated (and more expensive), when it's so easy to give tablets - my two wolf them down wrapped up in a sliver of liver pate! Also you should be able to get tablets very much cheaper from an internet pharmacy that does veterinary medicines and will sell prescription drugs. You just get a prescription from your vet and then order them from the pharmacy and post the prescription to them (for some medication, they will keep the prescription for you, but my vet won't/can't prescribe human drugs like gabapentin for more than one month at a time).

    The gabapentin dose seems very low - about 1mg according to your maths (unless it should be 7ml, not 0.7 - I find ml/mg conversion so confusing!) - but Oliver started on 100mg x 3 when he developed painful symptoms.

    Kate, Oliver and Aled

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    Charlie's gabapentin is dispensed as 100 mg in each ml. So he's have 70 mgs three times a day. So he could go up to 100 mgs three times per day.

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    Agree with Kate -- have never heard of this much fuss either from a vet to put omeprazole in solutions! -- why not just either get a prescription for small tablets if they are this small, or cut tablets, or buy over the counter? It is regularly on sale at the major pharmacies and is available as a generic. Sometimes prescription is still cheaper. It isn;t cheap but neither is it a really costly medication.

    I'd say it is very likely your dog will need to go up to 100mg 2x or 3x on gabapentin anyway -- don;t know of any that have ever stayed on smaller doses any length of time as the condition progresses/effectiveness of gabapentin weakens. Much easier and cheaper to get pills. If you are seeing symptoms I'd go to 100mg 3x and switch over to capsules as they are likely far cheaper and less fussy than oral solutions. On the other hand some like the solutions so to each his or her own.

    Shirley -- Vets internationally can't dispense gabapentin or Lyrica directly as far as I know at all, as neither is approved for vet use yet -- and if they did, they would almost certainly be more expensive than sourcing from various chemists! It is always cheaper in my experience to get a prescription even for vet meds from a vet and then buy them online from a verified source (many in the UK etc) -- significantly less expensive than paying through the vet who does another markup. I am actually thankful that at least with these more expensive meds I have the opportunity NOT to have to buy them from the vet!
    Karlin
    Cavaliers: Jaspar Leo Lily Tansy Libby (foster) Mindy (foster)
    In memory: Lucy
    Cavalier SM Infosite:www.smcavaliers.com

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    Karlin
    I agree entirely. In Canada there is no generic for Omeprazole and I'm told it's not available in tablets. The cost is $100.00 a month (not sure how many pounds that is). The gabapentin has been increased three times since January so will probably continue. The vet college here doesn't recommend Omeprazole or cimitidine for SM so my very cooperative vet is questioning its use. Another client with SM dogs questioned Charlie`s low dose of gabapentin too.

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