So she likely had an undiagnosed congenital PSS - that would explain her small size (despite being overweight) and if she had "failure to thrive" and the current state of her liver. The cholangitis could be the result of the gallstones blocking the biliary tree.
What antibiotics is she on for the bacterial infection? I think they often use metronidazole for liver disease.
A vet is never going to criticize another vet's treatment to a client. It just isn't ever going to happen. I would completely stop the Comfortan, but I perfectly understand if you are not comfortable doing that.
I'm so sorry to hear your news, but it is not unexpected. You are a wonderful owner to Megan. Remember that she is not afraid and lives in the present moment. You rescued her and gave her a happy life, and she loves you very much.
Pat





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