The first thing I would do is rule out is the easy stuff.
Does she wear a collar that might be bothering her? If so, maybe the collar is only worn when she goes outside. I would have her checked for an ear infection. As for the flea collar, I have never had any luck with them; gave up on them years ago. We use Frontline Plus at our house. If you think you have fleas, your vet could also give you a recommendation. If there are fleas in the house, you also need to take care of that. The last time I had fleas in the house was better than 20 years ago, so I am not at all up on what is out there for that. And finally is the really scary one: SM. If everything else checks out, then start educating yourself about SM.