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Thread: geneticist view of SM and inheritance

  1. #11
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    Thanks Karlin,

    I think it wil be most interesting to find out what is causing SM, I do think it is a genetic problem and whether it is a defective gene or a gene too few or too many will be really interesting. I wonder if they will also find out from the research whether SM clear parents can have an SM affected puppy. I know from one of the other groups that there is an SM clear bitch that has had an affected pup.

    I personally will be more than interested to know if a symptom free and MRI clear dog/bitch can actually carry SM that can be passed onto any offspring. For example people with a family history of haemohillia, the females are usually carriers whilst the males are sufferers.

    Hope I haven't confused anyone here....

  2. #12
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    This is what the last Rusbridge newsletter said:

    A number of dogs have a mild malformation but do not have syringomyelia
    Clinically affected offspring often have affected (clinically or sub-clinically) parents
    Clinically affected parents can produce ‘clear’ offspring
    The second point would seem to imply that affected offspring can come from clear parents.

    The newsletter is here: http://sm.cavaliertalk.com/smnewssum05.htm

    I do know that Clare says very definitely, a clear parent can produce affected offspring.
    Karlin
    Cavaliers: Jaspar Leo Lily Tansy
    In memory: Lucy
    Cavalier SM Infosite:www.smcavaliers.com

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